J Korean Neurol Assoc.
1990 Dec;8(2):318-324.
A Clinical Analysis in 12 Cases of Moyamoya Disease
- Affiliations
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- 1Department of Neurology, College of Medicine, Chonnam National University, Korea.
- 2Department of Neurosurgery, College of Medicine, Chonnam National university, Korea.
Abstract
- It is generally known that moyamoya disease is a disease showing typical angiographic findings such as bilateral stenosis or occlusion of the distal internal carotid arteries and the major branches with extensive parenchymal, leptomeningeal or transdural anastomosis. However, its etiology is still unknown. Chief clinical manifestations are transient ischemic attack, motor paresis, headache, altered mentality and seizure. Twelve angiographically proven cases of moyamoya disease in chonnam National University Hospital from 1983 to 1990 were analyzed with respect to clinical manifestations, findings of brain computed tomography, cerebral angiographic findings and outcomes. The results were as follows: 1) Sex ratio was 1:2 as 4 males to 8 females. 2) They were 2 juvenile form(aged 8-13 yrs) and 10 adult form(aged l9-59 yrs). 3) Transient ischemic attack(2 cases), hemiparesis (5 cases), headache(6 cases), altered mentality(4 cases), facial palsy(2 cases), aphasia(1 case) and neck stiffness(1 case) were shown as clinical anifestations. 4) In brain computed tomography, intraventricular hemorrhage(5 cases), intracerebral emorrhage(2 cases), subarachnoid hemorrhage(1 case), infarction(4 cases including 2 old infarction combined with hemorrhage), contrast enhanced tortuous moyamoya vessels only in brain base(1 case) and suprasellar tumor(1 case) were noted. 5) Brain magnetic resonance imaging was perfomed in 1 case. It revealed characteristic collateral vessels in brain base. 6) All cases showed the characteristic angiographic findings of moyamoya disease with different stage of the progression, In addition to moyamoya vessels, 2 cases of aneurysm and 1 case of diffuse internal carotid artery hypoplasia were found. 7) Some neurologic sequales were noted in two cases. One case expired due to recurret intraventricular hemorrhage.
