J Korean Rheum Assoc.  1994 Jan;1(1):71-76.

Chronic Cutaneous Lupus Erythematosus With Hematologic/serologic Abnormalities: Incomplete Systemic Lupus Erythematosus

Affiliations
  • 1Department of Dermatology, Hanyang University College of Medicine, Seoul, Korea.

Abstract


OBJECTIVE
Discoid erythema is most common skin lesions in chronic cutaneous lupus erythematosus (CCLE), and patients with multiple discold lesions occasionally transform into systemic lupus erythematosus (SLE). METHOD: Four patients of CCLE with 1 or 2 another criteria for the diagnosis of SLE (incomplete/latent SLE) were identified. With these patients, we undertook prospective studies regarding the response to treatment (topical corticosteroids/antimalarials) and the course of disease over a period of 3 years.
RESULTS
During the past 3 years, all of the patients continued to be stable, and only experienced minor exacervations of cutaneous and/or systemic symptoms. They showed no evidences of complete remission or developing additional criteria to determine SLE.
CONCLUSION
It is suggested that incomplete/latent SLE with discold cutaneous lesions infrequently evolve to SLE, and it would appear that our cases probably have good prognosis, without or minimum systemic involvements.

Keyword

Lupus erythematosus; Discoid cutaneous lesion; Incomplete SLE; Clinical course

MeSH Terms

Diagnosis
Erythema
Humans
Lupus Erythematosus, Cutaneous*
Lupus Erythematosus, Systemic*
Prognosis
Prospective Studies
Skin
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