Korean J Anesthesiol.  1980 Mar;13(1):28-33.

Anesthetic Management for the Resection of Pheochromocytoma

• Kim SD
• Chang SH
• Lee SC
• Lee KI
• Kwak IY

Abstract

Inhalation anesthetics, particularly the hydrocarbons and cyclopropane. lower the threshold to the arrhythmogenic activity of catecholamines. This interaction is of concern during the resection of a pheochromocytoma when the surgically-induced release of large amounts of norepinephrine and epinephrine from tumors sets the stage for ventricular arrhythmia by a direct effect on the myocardium together with an increase in blood pressure. In this communication, anesthesia was performed with N2,O-O2,-halothane. In addition patient was managed successfully, using d-tubocurarine, phentolamine (Regitine) and propranolol (Inderal). For the next same case, enflurane is recommended because of absence of flammability, arrhythmogenic activity and nephrotoxity. etc.

MeSH Terms

Anesthesia
Anesthetics, Inhalation
Arrhythmias, Cardiac
Blood Pressure
Catecholamines
Enflurane
Epinephrine
Humans
Hydrocarbons
Myocardium
Norepinephrine
Phentolamine
Pheochromocytoma*
Propranolol
Tubocurarine
Anesthetics, Inhalation
Catecholamines
Enflurane
Epinephrine
Hydrocarbons
Norepinephrine
Phentolamine
Propranolol
Tubocurarine