- Epinephrine-Induced Digital Vasospasm Reversed by a Phentolamine-Papaverine-Alprostadil Complex: A Case Report
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Koh SH, You Y, Kim JS, Lee DC, Roh SY, Lee KJ, Hong MK
- KMID: 2464470
- Arch Hand Microsurg.
- 2019 Dec;24(4):345-350.
- doi: 10.12790/ahm.2019.24.4.345
Epinephrine is widely used to treat severe anaphylaxis. However, the accidental injection of epinephrine into regions containing terminal arteries, such as digits, may cause severe vasospasm, leading to digital ischemia,... -
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- Participation of Opioid Pathway in the Central Antinociceptive Effects of Eugenol
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Kang SH, Kang SW, Kim JH, Kim HY, Ryu HS, Bae SY, Oh JA, Lee JH, Hyun JH, Ahn DK
- KMID: 2437352
- Int J Oral Biol.
- 2018 Sep;43(3):147-153.
- doi: 10.11620/IJOB.2018.43.3.147
The aim of the present study was to evaluate the central antinociceptive effects of eugenol after intraperitoneal administration. Experiments were carried out using male Sprague-Dawley rats. Subcutaneous injection of 5%... -
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- Chronic stress enhances progression of periodontitis via alpha1-adrenergic signaling: a potential target for periodontal disease therapy
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Lu H, Xu M, Wang F, Liu S, Gu J, Lin S
- KMID: 2155383
- Exp Mol Med.
- 2014 Oct;46(10):e118.
- doi: 10.1038/emm.2014.65
This study assessed the roles of chronic stress (CS) in the stimulation of the sympathetic nervous system and explored the underlying mechanisms of periodontitis. Using an animal model of periodontitis... -
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- Characteristics of Diprophylline-Induced Bidirectional Modulation on Rat Jejunal Contractility
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Liu FF, Chen DP, Xiong YJ, Lv BC, Lin Y
- KMID: 2285490
- Korean J Physiol Pharmacol.
- 2014 Feb;18(1):47-53.
- doi: 10.4196/kjpp.2014.18.1.47
In this study, we propose that diprophylline exerts bidirectional modulation (BM) on the isolated rat jejunal segment depending on its contractile state. The results supported the hypothesis. Diprophylline (20 microM)... -
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- Depressor action and vasorelaxation of methylene chloride fraction extracted from Rubus coreanum
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Yu BS, Choi MS, Lim DY
- KMID: 2380256
- Clin Hypertens.
- 2014 ;20(3):6.
- doi: 10.1186/s40885-014-0006-1
INTRODUCTION: The present study was designed to examine whether methylene chloride (CH2Cl2) fraction extracted from Rubus coreanum affects the contractility of the isolated thoracic aortic strips and blood pressure of... -
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- Inhibitory effect of Suaeda asparagoides (Miq.) extract on the motility of rat gastric antrum is mediated by beta-adrenoceptor
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Endale M, Song JC, Rhee MH, Liu KH, Kim TK, Kwon JG, Park KS, Chung KM, Kim TW
- KMID: 1444964
- Lab Anim Res.
- 2011 Dec;27(4):317-325.
- doi: 10.5625/lar.2011.27.4.317
Suaeda asparagoides (Miq.) has long been used as a Korean folk herbal medicine for the treatment of functional gastrointestinal disorders. However, reports on its pharmacological activity on gastrointestinal motility are... -
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- The Effect of Autonomic Nerve System on Neurotensin Induced Motility in Isolated, Vascularly Perfused Rat Colon
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Ji JH, Kim SM, Seo E, Cho YS, Yoo SH, Han JH, Chae HB, Park SM, Youn SJ
- KMID: 2284934
- Intest Res.
- 2010 Dec;8(2):162-171.
- doi: 10.5217/ir.2010.8.2.162
BACKGROUND/AIMS: Although neurotensin (NT) stimulates colon motility and the passage of intestinal contents, the associated mechanism of action remains unclear. The objective of this study was to investigate the effects... -
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- Usefulness of Awake Anesthesia in Flexor Tendon Surgery
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Shim BK, Jung SG, Choi HJ, Park ES, Tark MS
- KMID: 2120581
- J Korean Soc Plast Reconstr Surg.
- 2010 Nov;37(6):795-800.
PURPOSE: According to various medical publications, it is believed that epinephrine should not be injected in fingers. However numerous articles show the successful use of local anesthetic with epinephrine in... -
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- Involvement of Selective Alpha-2 Adrenoreceptor in Sympathetically Maintained Pain
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Park CH, Yong A, Lee SH
- KMID: 2339886
- J Korean Neurosurg Soc.
- 2010 Jun;47(6):420-423.
OBJECTIVE: Peripheral nerve injury often leads to neuropathic pain, which is characterized by burning pain, allodynia, and hyperalgesia. The role of the sympathetic nervous system in neuropathic pain is a... -
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- The mechanism of action of neuropeptide Y in rat colonic motility
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Nah BK, Jeon WJ, You IY, Chae HB, Park SM, Youn SJ, Ko BS
- KMID: 2256137
- Korean J Med.
- 2008 Aug;75(2):186-193.
BACKGROUND/AIMS: Neuropepetide Y (NPY) is involved in the regulation of several gut functions, but the neuronal action of NPY has not been fully investigated. This study was designed to investigate... -
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- The Mechanism of 5-Hydroxytryptamine4 (5-HT4) Receptor Partial Agonist (Tegaserod) on Rat Colonic Motility
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Kim MS, Ko BS, Oh SJ, Han JH, Jeon WJ, Chae HB, Park SM, Youn SJ
- KMID: 2307442
- Korean J Neurogastroenterol Motil.
- 2008 Jun;14(1):24-31.
BACKGROUNDS/AIM: A 5-Hydroxytrypatmine4 (5-HT4) partial agonist, Tegaserod (Tega), stimulated the peristaltic reflex in vitro and increases canine intestinal and colonic motility and transit. The objectives of this study were to... -
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- Medical Treatment of the Female Sexual Dysfunction
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Min KS
- KMID: 2298613
- Korean J Androl.
- 2007 Apr;25(1):1-8.
During the past 10 years, there have been many studies in the field of female sexual function and dysfunction. Studies of genital hemodynamic-related sexual arousal, contractility of the genital tissue,... -
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- The Mechanism of Action of Peptide YY on Colonic Motility
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Choi KW, Youn SJ, Han JH, Jeon WJ, Chae HB, Park SM
- KMID: 2307506
- Korean J Neurogastroenterol Motil.
- 2005 Dec;11(2):142-151.
BACKGROUND/AIMS: The mechanism by which peptide YY (PYY) stimulates colonic motility has not yet been fully elucidated. The aim of this study was to investigate PYY's mechanism of action on... -
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- The Action of Substance P on the Colonic Motility in Rat Colon
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Choi JH, Nah BK, Bae SS, Choi KW, Chae HB, Park SM, Youn SJ
- KMID: 2255872
- Korean J Neurogastroenterol Motil.
- 2004 Jun;10(1):63-71.
BACKGROUND/AIMS: The mechanism by which substance P (SP) stimulates colonic motility has not yet been fully elucidated. The study objective was to investigate the action mechanism of SP on isolated... -
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- Comparison of the Effects Elicited by Bromocriptine and SKF-38393 on Transmembrane Action Potential in Rat Atrial Fibers
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Ju JM, Kim HH, Piao LH, Park HW, Cho JG, Kim JH
- KMID: 1973359
- Chonnam Med J.
- 2004 Jun;40(2):61-70.
Effects of two dopaminergic agonists bromocriptine (BRO) and SKF-38393 (SKF) on electrophysiology of the ischemia-simulated rat atrial fibers with superfusion of modified physiologic salt solution (MPSS) were examined. All the... -
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- Erectile Response of Intracavernous Injection of New Triple Agents, Chlorpromazine, Papaverine, and Alprostadil
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Lee YS, Kim SC
- KMID: 2293569
- Korean J Urol.
- 2003 Nov;44(11):1121-1123.
PURPOSE: This study was aimed to compare the erectile response when phentolamine of intracavernous trimix(papaverine, phentolamine, alprostadil) was replaced with chlorpromazine. MATERIALS AND METHODS: A total of 65 patients with erectile... -
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- Multicenter Study on the Efficacy and Safety of Intracavernous 'TM' (Standro(R)) for the Treatment of Erectile Dysfunction in Korean
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Kim SC, Kim DS, Kim SW, Kim JH, Kim JJ, Moon KH, Park KS, Park NC, Park JK, Park JH, Park HS, Park HY, Paick JS, Seo KK, Seo SI, Suh JK, Sohn IC, Shin DJ, Ahn TY, Yoon CJ, Lee SW, Lee WC, Jung GW, Choi HK, Hong JH, Hwang TK
- KMID: 2293457
- Korean J Urol.
- 2003 Jul;44(7):702-707.
PURPOSE: To evaluate the efficacy and safety of an intracavernous injection of lyophilized papaverine/phentolamine/alprostadil (Standro(R)) for the treatment of erectile dysfunction (ED) in Koreans. MATERIALS AND METHODS: 249 men (>20... -
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- Chemical Stability of Lyophilized Papaverine/Phentolamine/Alprostadil (Standro(R))
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Kim SC, Shim YW, Sung JY
- KMID: 2145845
- Korean J Androl.
- 2003 Apr;21(1):23-26.
PURPOSE: To investigate the chemical stability of papaverine/phentolamine/alprostadil (Standro(R)) used for intracaver nous injection in patients with erectile dysfunction. MATERIALS AND METHODS: Samples of lyophilized Standro(R) were stored at room temperature (25+/-2... -
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- Experience of Intracorporeal Injection Therapy in the Era of Oral Sildenafil
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Park SH, Kang TW, Park K
- KMID: 2172367
- Chonnam Med J.
- 2003 Mar;39(1):37-40.
The aim of this study was to evaluate the outcome of intracorporeal injection (ICI) therapy in the era of oral sidenafil for erectile dysfunction. A total of 118 impotent patients... -
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- Effects of Kanagawa Hemolysin on Blood Pressure and Arterial Tone in Rats
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Kim YM
- KMID: 2071584
- Korean J Physiol Pharmacol.
- 2002 Aug;6(4):225.
Kanagawa hemolysin (KH), an exotoxin produced from Kanagawa phenomenon-positive Vibrio parahemolyticus, has been shown to possess various biological activities including hemolysis, enterotoxicity, cytotoxicity, and cardiotoxicity. The aim of this study... -
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