Korean J Cytopathol.  2006 Mar;17(1):63-68.

Fine Needle Aspiration Cytology of Inflammatory Myofibroblastic Tumor of Lung: A Case Report

• Park G
• Lee K
• Lee SM
• Lee KY
• Shim SI
• Kang CS
• Lee YS

Abstract

Inflammatory myofibroblastic tumor (IMT), normally referred to as inflammatory pseudotumor, is a fairly rare condition. Fine needle aspiration cytology (FNAC) of IMT has only rarely been reported. Here, we describe one such case of pulmonary inflammatory myofibroblastic tumor. A 30-year-old man presented with a 2.8cm-sized mass in his lung. Chest CT revealed a well defined, poorly enhancing mass. FNAC showed some fascicular or swirled clusters of spindle cells, admixed with occasional inflammatory cells and foamy histiocytes. The majority of the tumor cells evidenced bland, elongated nuclei, but infrequent pleomorphic nuclei. Some of the tumor cells evidenced nuclear grooves and intranuclear inclusions. Although the cytological differentiation of IMT from malignant lesions is not immensely problematic, due to the general paucity of cytological and nuclear atypia, a definite cytological diagnosis of IMT cannot be rendered simply by FNAC. Therefore, a diagnosis of IMT may be suggested via exclusive diagnosis.

Keyword

Inflammatory pseudotumor; Lung; Fine needle aspiration cytology

MeSH Terms

Adult
Biopsy, Fine-Needle*
Diagnosis
Granuloma, Plasma Cell
Histiocytes
Humans
Intranuclear Inclusion Bodies
Lung*
Myofibroblasts*
Tomography, X-Ray Computed