Korean J Gastrointest Endosc.  1999 Feb;19(1):1-8.

Risk Factors Associated with Rebleeding and Recurrence Following Endoscopic Variceal Ligation

• Oh SY
• Lee JH
• Koh KC
• Paik SW
• Lee SH
• Choi MS
• Lee JK
• Lee KT
• Rhee PL
• Kim JJ
• Rhee JC
• Choi KW

Abstract

the first EVL was associated with rebleeding (p=0.01); whereas, age, Child class, grade and extent of varices, presence of gastric varices and/or portal hypertensive gastropathy, total number of bands and sessions for successful EVL were not (p >0.05). Persistence of esophageal ulcer at 2 weeks after the first EVL was associated with rebleeding also in multivariate analysis (relative risk 5.87, p=0.01). 3) In univariate analysis, grade (p=0.01) and extent (p=0.01) of varices were related to recurrence; whereas, age, Child class, presence of gastric varices and/or portal hypertensive gastropathy, total number of bands and sessions for successful EVL were not (p >0.05). In multivariate analysis, grade of varices was the only risk factor associated with recurrence (relative risk 3.76, p=0.01). CONCLUSIONS: 1) Persistence of esophageal ulcer at second week after the first EVL was associated with rebleeding. 2) Frequent follow-up endoscopic examinations are necessary in patients who present with high grade of varices since risk of recurrence is high even after successful EVL.

Keyword

Esophageal varices; Endoscopic variceal ligation; Rebleeding; Recurrence

MeSH Terms

Child
Esophageal and Gastric Varices
Follow-Up Studies
Humans
Ligation*
Multivariate Analysis
Recurrence*
Risk Factors*
Ulcer
Varicose Veins