Korean J Gastrointest Endosc.  1989 Nov;9(2):187-193.

Three Cases of Gastric Pseudolymphoma


Gastric pseudolymphoma can be defined as a benign proliferation of lymphoid tissue and is also called the lymphoid hyperplasia or reactive lymphoreticular hyperplasia of the stomach. This lesion has been described in the orbital area, skin, salivary glands, mediastinum and other organs. The etiology of this disease is unknown but chronic inflammation and ulceration have been proposed as the etiologic mechanism in many cases. Most patients exhibit chronic, nonspecific, mild symptoms with the vast majority having symptoms for more than 1 year before undergoing diagnosis and treatment. Unfortunately, upper GI radiography rarely clarifies the diagnosis and gastroacopy is ineffective in establishing the diagnosis of pseudolpnphoma. Therefare, gastric resection is the only sure way to diagnose gastric pseudolympboma, as well as providing curitive therapy in most cases because of its possible malignant potential. There is no typical gross appearance of gastric pseudolymphoma and histologic diagoosis is essential. Smaller tumor size, infiltration with small, round mature lymphoeytos and various inflammatory cells, and formation of a true lymphoid germinal center favor a diagnosis of pseudolymphoma, We report 3 cases of histopathologically confirmed gastric pseudolymphoma after gastrectomy, which were initially suspected to be gastric lymphoma and early gastric cancer

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