Korean J Med.
2003 Nov;65(5):604-609.
Systemic lupus erythematosus accompanied with idiopathic inflammatory myopathy: report of 2 cases
- Affiliations
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- 1Department of Internal Medicine, College of Medicine, Dankook University, Cheonan, Korea. hanks22@dankook.ac.kr
- 2Department of Diagnostic Radiology, College of Medicine, Dankook University, Cheonan, Korea.
- 3Department of Pathology, College of Medicine, Dankook University, Cheonan, Korea.
Abstract
- Generalized myalgia and muscle tenderness are relatively common during exacerbations in patients with systemic lupus erythematosus (lupus), and inflammatory myositis involving the proximal muscles occurs in 5~11% of patients during the course of the disease. However, patients with overlap syndrome of lupus and idiopathic inflammatory myopathy have been not that frequent. We described 2 patients with overlap syndrome of these two diseases. Patient 1 was a 27-year-old female patient concurrently having lupus and dermatomyositis. She manifested the characteristic skin rash for dermatomyositis such as heliotrope rash. Patient 2 was a 32-year-old female patient concurrently having lupus and polymyositis, in whom the disease-specific autoantibodies for lupus or idiopathic inflammatory myopathy such as anti-ds DNA antibody, anti-Sm antibody and anti-Jo-1 antibody were positive.
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