Res Vestib Sci.  2014 Jun;13(2):53-56.

A Case of Creutzfeldt-Jakob Disease Presenting Mainly with Abnormal Eye Movements

Affiliations
  • 1Department of Neurology, Soonchunhyang University Bucheon Hospital, Soonchunhyang University College of Medicine, Bucheon, Korea. xorudoc@schmc.ac.kr

Abstract

Creutzfeldt-Jakob disease (CJD) is a human prion disease with rapidly progressive neurodegeneration. The major clinical manifestations of CJD include mental deterioration, myoclonus, cerebellar dysfunction, and neuro-ophthalmic symptoms and signs. However, abnormal eye movements as an early sign of CJD are rare. We report a 49-year-old man with periodic alternating nystagmus in early disease course.

Keyword

Creutzfeldt-Jakob syndrome; Fixation, ocular; Nystagmus, pathologic

MeSH Terms

Cerebellar Diseases
Creutzfeldt-Jakob Syndrome*
Eye Movements*
Fixation, Ocular
Humans
Middle Aged
Myoclonus
Nystagmus, Pathologic
Prion Diseases
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