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Region-Specific Differences in the Apoe4-dependent Response to Focal Brain Injury

Lee SE, Yang H, Sung Y, Kim Y, Park SA

  • KMID: 2519890
  • Exp Neurobiol.
  • 2021 Aug;30(4):285-293.
  • doi: 10.5607/en21022
Apolipoprotein E (apoE) plays a role in various physiological functions including lipid transport, synaptic plasticity, and immune modulation. Epidemiological studies suggest that the apoE4 allele increases the risk of post-traumatic sequelae....
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Longitudinal Observation of Early-Onset Alzheimer’s Disease Dementia with Positive CSF Biomarkers/Negative Amyloid-β Positron-Emission Tomography

Kim MH, Lee J, Kim HN, Shin IJ, Lee K, Kim YS, Lee SM, Park SA, Moon SY

We report a 61-year-old woman with clinical course for Alzheimer’s disease (AD) dementia and discordant amyloid-β positron-emission tomography (PET) and cerebrospinal fluid biomarkers. Brain magnetic resonance imaging revealed remarkable atrophy...
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Endoscopically Applied Biodegradable Stent in a Rabbit Model of Pediatric Tracheomalacia

Choi JS, Seok J, Eom MR, Jung E, Park SA, Joo SM, Jun YJ, Son KW, Kwon SK

Objectives. A polydioxanone (PDO) stent was developed to treat tracheomalacia in pediatric patients. However, its safety and efficacy need to be verified in animal studies before clinical trials in patients...
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The Effect of a Breathing Relaxation Therapy for Pregnant Women with Preterm Labor Pain: a Systematic Review and Meta-Analysis

Park SA

To evaluate the effects of abdominal breathing relaxation therapy on anxiety, stress, pain for pregnant women with preterm labor pain. Electronic databases, including PubMed, OVID MEDLINE, RISS, Google Scholar and...
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Hyaluronic Acid Coating on Hydrophobic Tracheal Scaffold Enhances Mesenchymal Stem Cell Adhesion and Tracheal Regeneration

Choi JS, Lee MS, Kim J, Eom MR, Jeong EJ, Lee M, Park SA, Jeong JH, Kwon SK

BACKGROUND: Long segmental tracheal repair is challenging in regenerative medicine due to low adhesion of stem cells to tracheal scaffolds. Optimal transplantation of stem cells for tracheal defects has not...
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Relationship between Career Success Perception and Protean Career Management Behavior in Clinical Dental Hygienists

Park SA, Cho YS

Background: Career success is the psychological achievement associated with an individual’s work. Protean career management behavior is the behavior of managing individual careers in order to achieve individual career goals....
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Development and effects of a labor nursing education program using a high-fidelity simulator for nursing students in Korea

Park SA, Kim HY

Purpose: This study was conducted to investigate the effects of an education program using a high-fidelity simulator of labor and delivery on nursing knowledge, critical thinking, and clinical performance among...
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Executive Summary of the 2019 International Conference of Korean Dementia Association: Exploring the Novel Concept of Alzheimer's Disease and Other Dementia: a Report from the Academic Committee of the Korean Dementia Association

Park KH, Lim JS, Seo SW, Jeong Y, Noh Y, Koh eH, Bae Js, Park SA, Yang SJ, Kim HJ, Chin J, Roh Jh, An SSA, Korean Dementia Association

Because of repeated failures of clinical trials, the concept of Alzheimer's disease (AD) has been changing rapidly in recent years. As suggested by the National Institute on Aging and the...
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Diosmetin and Its Glycoside, Diosmin, Improve Atopic DermatitisLike Lesions in 2,4-Dinitrochlorobenzene-Induced Murine Models

Park Sa, Bong SK, Lee JW, Park NJ, Choi Y, Kim SM, Yang MH, Kim YK, Kim SN

Naturally derived diosmetin and its glycoside diosmin are known to be effective in treating inflammatory disease. This study was performed to determine whether diosmin and diosmetin have the effect of...
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The Impact of Grit on University Student's Core Competency in Dental Hygiene Students

Park SA, Cho YS

BACKGROUND: Recently, competency-based education has been reorganized in the dental hygiene curriculum. In education, non-cognitive factors are emphasized. Grit, the non-cognitive ability to persevere to achieve an individual’s long-term goals,...
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Genetic Profiles Associated with Chemoresistance in Patient-Derived Xenograft Models of Ovarian Cancer

Li LY, Kim HJ, Park SA, Lee SH, Kim LK, Lee JY, Kim S, Kim YT, Kim SW, Nam EJ

PURPOSE: Recurrence and chemoresistance (CR) are the leading causes of death in patients with high-grade serous carcinoma (HGSC) of the ovary. The aim of this study was to identify genetic...
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Cerebrospinal Fluid Levels of β-Amyloid 40 and β-Amyloid 42 are Proportionately Decreased in Amyloid Positron-Emission Tomography Negative Idiopathic Normal-Pressure Hydrocephalus Patients

Kim HJ, Lim TS, Lee SM, Kim TS, Kim Y, An YS, Youn YC, Park SA, Chang J, Moon SY

BACKGROUND AND PURPOSE: Cerebrospinal fluid (CSF) biomarkers of Alzheimer's disease (AD) could be misleading in idiopathic normal-pressure hydrocephalus (iNPH). We therefore investigated the CSF biomarkers in 18F-florbetaben amyloid-negative positron-emission tomography...
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Primary Cardiac Hemangioendothelioma in an Infant: A Case Report

Seo JW, Song MK, Park SH, Park HE, Park SA

Primary cardiac tumors are rare, with a prevalence of 0.001–0.2%. Among such tumors, cardiac hemangioendotheliomas are some of the most uncommon. In Korea, there have been no reports of hemangioendothelioma...
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Factors Influencing Exposure to Secondhand Smoke: Passive Inhalation in Student Nurses

Park SA, Lee DH, Lim HS

OBJECTIVES: To examine the factors affecting passive exposure to secondhand smoke (SHS) in non-smoking student nurses. METHODS: A cross-sectional study was performed in 196 college students who had not smoked cigarettes...
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Management of Elderly Patients with Spinal Disease: Interventional Nonsurgical Treatment

Park SA

Owing to the upward shift in age structure, there is an increasing number of spinal diseases specific to elderly patients. Elderly spinal patients typically have a poor general condition with...
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A Comparison Study of Cilostazol and Aspirin on Changes in Volume of Cerebral Small Vessel Disease White Matter Changes: Protocol of a Multicenter, Randomized Controlled Trial

Han HJ, Kim BC, Youn YC, Jeong JH, Kim JH, Lee JH, Park KH, Park KW, Kim EJ, Oh MS, Shim YS, Park HY, Yoon B, Yoon SJ, Cho SJ, Park KC, Na DL, Park SA, Lee JM, Choi SH

BACKGROUND AND PURPOSE: Cerebral small vessel disease (CSVD) is the most common cause of vascular dementia and a major contributor to mixed dementia. CSVD is characterized by progressive cerebral white...
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Depression and Fear about Maturation in Girls with Precocious Puberty and Depression and Anxiety in Their Mothers

Lee MJ, Baek SH, Park SA

PURPOSE: This study investigated depression and anxiety in girls with precocious puberty and in their mothers. METHOD: This study recruited 75 girls treated with a gonadotropin-releasing hormone agonist (GnRHa) and their...
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Comparison of Clinical Features and Outcomes in Epithelial Ovarian Cancer according to Tumorigenicity in Patient-Derived Xenograft Models

Eoh KJ, Chung YS, Lee SH, Park SA, Kim HJ, Yang W, Lee IO, Lee JY, Cho H, Chay DB, Kim S, Kim SW, Kim JH, Kim YT, Nam EJ

PURPOSE: Although the use of xenograft models is increasing, few studies have compared the clinical features or outcomes of epithelial ovarian cancer (EOC) patients according to the tumorigenicity of engrafted...
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Crossed Cerebellar Diaschisis: Risk Factors and Correlation to Functional Recovery in Intracerebral Hemorrhage

Sin DS, Kim MH, Park SA, Joo MC, Kim MS

OBJECTIVE: The purpose of this study is to investigate predictors of crossed cerebellar diaschisis (CCD), and the effects of CCD on functional outcomes including motor function, activities of daily living,...
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Characteristics of Residual Symptoms in Korean Patients with Major Depressive Disorder: A Validation Study for the Korean Version of Depression Residual Symptom Scale

Park SA, Jeon SW, Yoon HK, Yoon SY, Shin C, Ko YH

OBJECTIVE: Residual symptoms of depression are related to more severe and chronic course of functional impairment with higher risk of relapse. The objective of this study was to validate, and...
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