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Influence of Sensory Impairments on Incidence of Dementia in the Korean Population

Oh Gh, Jhoo JH, Park Sa, Jang JW, Kim Y, Choe YM, Byeon G

Objective Previous studies have shown the influence of visual and auditory sensory impairment on dementia incidence. In this study, we tested the hypothesis that the incidence of dementia will increase...
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Assessment of Esophageal Reconstruction via Bioreactor Cultivation of a Synthetic Scaffold in a Canine Model

Kim IG, Wu Y, Park SA, Choi JS, Kwon SK, Choi SH, Jung KC, Shin JW, Chung EJ

Objectives. Using tissue-engineered materials for esophageal reconstruction is a technically challenging task in animals that requires bioreactor training to enhance cellular reactivity. There have been many attempts at esophageal tissue...
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The first reported hepatitis E outbreak in a food manufacturing factory: Korea, 2022

Yeom H, Seo S, Yoon Y, Lee J, Han MG, Lee DY, Park SW, Park SA, Jeong SH, Gwack J

Objectives: On February 16, 2022, 12 cases of hepatitis E virus (HEV) infection were reported in a food manufacturing factory in Korea. The aim of this study was to identify...
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Progression of Hashimoto’s Thyroiditis to Graves’ Disease: a Report of Two Pediatric Cases

Yu JH, Park SA

Graves’ disease and Hashimoto’s thyroiditis are the most common types of autoimmune thyroid disease. However, these two diseases were previously considered as separate and distinct. Recent studies have shown that...
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Promising Blood Biomarkers for Clinical Use in Alzheimer’s Disease: A Focused Update

Park SA, Jang YJ, Kim MK, Lee SM, Moon SY

Alzheimer’s disease (AD) is the most-common cause of neurodegenerative dementia, and it is characterized by abnormal amyloid and tau accumulation, which indicates neurodegeneration. AD has mostly been diagnosed clinically. However,...
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The Change in Circadian Rhythms in P301S Transgenic Mice is Linked to Variability in Hsp70-related Tau Disaggregation

Han SM, Jang YJ, Kim EY, Park SA

  • KMID: 2531123
  • Exp Neurobiol.
  • 2022 Jun;31(3):196-207.
  • doi: 10.5607/en22019
Circadian disruption often involves a neurodegenerative disorder, such as Alzheimer’s disease or frontotemporal dementia, which are characterized by intraneuronal tau accumulations. The altered sleep pattern and diurnal rhythms in these...
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Region-Specific Differences in the Apoe4-dependent Response to Focal Brain Injury

Lee SE, Yang H, Sung Y, Kim Y, Park SA

  • KMID: 2519890
  • Exp Neurobiol.
  • 2021 Aug;30(4):285-293.
  • doi: 10.5607/en21022
Apolipoprotein E (apoE) plays a role in various physiological functions including lipid transport, synaptic plasticity, and immune modulation. Epidemiological studies suggest that the apoE4 allele increases the risk of post-traumatic sequelae....
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Longitudinal Observation of Early-Onset Alzheimer’s Disease Dementia with Positive CSF Biomarkers/Negative Amyloid-β Positron-Emission Tomography

Kim MH, Lee J, Kim HN, Shin IJ, Lee K, Kim YS, Lee SM, Park SA, Moon SY

We report a 61-year-old woman with clinical course for Alzheimer’s disease (AD) dementia and discordant amyloid-β positron-emission tomography (PET) and cerebrospinal fluid biomarkers. Brain magnetic resonance imaging revealed remarkable atrophy...
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Endoscopically Applied Biodegradable Stent in a Rabbit Model of Pediatric Tracheomalacia

Choi JS, Seok J, Eom MR, Jung E, Park SA, Joo SM, Jun YJ, Son KW, Kwon SK

Objectives. A polydioxanone (PDO) stent was developed to treat tracheomalacia in pediatric patients. However, its safety and efficacy need to be verified in animal studies before clinical trials in patients...
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The Effect of a Breathing Relaxation Therapy for Pregnant Women with Preterm Labor Pain: a Systematic Review and Meta-Analysis

Park SA

To evaluate the effects of abdominal breathing relaxation therapy on anxiety, stress, pain for pregnant women with preterm labor pain. Electronic databases, including PubMed, OVID MEDLINE, RISS, Google Scholar and...
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Hyaluronic Acid Coating on Hydrophobic Tracheal Scaffold Enhances Mesenchymal Stem Cell Adhesion and Tracheal Regeneration

Choi JS, Lee MS, Kim J, Eom MR, Jeong EJ, Lee M, Park SA, Jeong JH, Kwon SK

BACKGROUND: Long segmental tracheal repair is challenging in regenerative medicine due to low adhesion of stem cells to tracheal scaffolds. Optimal transplantation of stem cells for tracheal defects has not...
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Relationship between Career Success Perception and Protean Career Management Behavior in Clinical Dental Hygienists

Park SA, Cho YS

Background: Career success is the psychological achievement associated with an individual’s work. Protean career management behavior is the behavior of managing individual careers in order to achieve individual career goals....
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Diosmetin and Its Glycoside, Diosmin, Improve Atopic DermatitisLike Lesions in 2,4-Dinitrochlorobenzene-Induced Murine Models

Park Sa, Bong SK, Lee JW, Park NJ, Choi Y, Kim SM, Yang MH, Kim YK, Kim SN

Naturally derived diosmetin and its glycoside diosmin are known to be effective in treating inflammatory disease. This study was performed to determine whether diosmin and diosmetin have the effect of...
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Development and effects of a labor nursing education program using a high-fidelity simulator for nursing students in Korea

Park SA, Kim HY

Purpose: This study was conducted to investigate the effects of an education program using a high-fidelity simulator of labor and delivery on nursing knowledge, critical thinking, and clinical performance among...
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Executive Summary of the 2019 International Conference of Korean Dementia Association: Exploring the Novel Concept of Alzheimer's Disease and Other Dementia: a Report from the Academic Committee of the Korean Dementia Association

Park KH, Lim JS, Seo SW, Jeong Y, Noh Y, Koh eH, Bae Js, Park SA, Yang SJ, Kim HJ, Chin J, Roh Jh, An SSA, Korean Dementia Association

Because of repeated failures of clinical trials, the concept of Alzheimer's disease (AD) has been changing rapidly in recent years. As suggested by the National Institute on Aging and the...
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A Comparison Study of Cilostazol and Aspirin on Changes in Volume of Cerebral Small Vessel Disease White Matter Changes: Protocol of a Multicenter, Randomized Controlled Trial

Han HJ, Kim BC, Youn YC, Jeong JH, Kim JH, Lee JH, Park KH, Park KW, Kim EJ, Oh MS, Shim YS, Park HY, Yoon B, Yoon SJ, Cho SJ, Park KC, Na DL, Park SA, Lee JM, Choi SH

BACKGROUND AND PURPOSE: Cerebral small vessel disease (CSVD) is the most common cause of vascular dementia and a major contributor to mixed dementia. CSVD is characterized by progressive cerebral white...
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The Impact of Grit on University Student's Core Competency in Dental Hygiene Students

Park SA, Cho YS

BACKGROUND: Recently, competency-based education has been reorganized in the dental hygiene curriculum. In education, non-cognitive factors are emphasized. Grit, the non-cognitive ability to persevere to achieve an individual’s long-term goals,...
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Genetic Profiles Associated with Chemoresistance in Patient-Derived Xenograft Models of Ovarian Cancer

Li LY, Kim HJ, Park SA, Lee SH, Kim LK, Lee JY, Kim S, Kim YT, Kim SW, Nam EJ

PURPOSE: Recurrence and chemoresistance (CR) are the leading causes of death in patients with high-grade serous carcinoma (HGSC) of the ovary. The aim of this study was to identify genetic...
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Cerebrospinal Fluid Levels of β-Amyloid 40 and β-Amyloid 42 are Proportionately Decreased in Amyloid Positron-Emission Tomography Negative Idiopathic Normal-Pressure Hydrocephalus Patients

Kim HJ, Lim TS, Lee SM, Kim TS, Kim Y, An YS, Youn YC, Park SA, Chang J, Moon SY

BACKGROUND AND PURPOSE: Cerebrospinal fluid (CSF) biomarkers of Alzheimer's disease (AD) could be misleading in idiopathic normal-pressure hydrocephalus (iNPH). We therefore investigated the CSF biomarkers in 18F-florbetaben amyloid-negative positron-emission tomography...
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Primary Cardiac Hemangioendothelioma in an Infant: A Case Report

Seo JW, Song MK, Park SH, Park HE, Park SA

Primary cardiac tumors are rare, with a prevalence of 0.001–0.2%. Among such tumors, cardiac hemangioendotheliomas are some of the most uncommon. In Korea, there have been no reports of hemangioendothelioma...
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