Korean J Thorac Cardiovasc Surg.  2002 Oct;35(10):768-772.

Extranodal Rosai-Dorfman Disease in Mediastinum: A Case Report

• Choe JW
• Oh TY
• Cho EY
• Chang WH

Abstract

Sinus histiocytosis with massive lymphadenopathy or Rosai-Dorfman disease(RDD) is a rare type of histiocytosis syndrome, that presents in its most typical form as massive, painless, bilateral lymph node enlargement in the neck during the first or second decade of life. The disease involves extranodal site in over 25% to 43% of the cases, however cases of extranodal RDD without nodal disease have rarely been reported. The involved sites of extranodal RDD have been reported various that were orbit, ocular adnexae, head and neck, upper respiratory tract, breast, gastrointestinal tract, CNS, etc. A 35 year-old man was present with pleural pain on left anterior chest and anterior mediastinal mass, that underwent an excision to remove the suspected invasive thymoma, and the diagnosis was confirmed to extranodal Rosai-Dorfman disease.

Keyword

Histiocytosis; Mediastinal neoplasm

MeSH Terms

Adult
Breast
Diagnosis
Gastrointestinal Tract
Head
Histiocytosis
Histiocytosis, Sinus*
Humans
Lymph Nodes
Mediastinal Neoplasms
Mediastinum*
Neck
Orbit
Respiratory System
Thorax
Thymoma