Korean J Perinatol.
2005 Mar;16(1):23-30.
Association between Hematologic Abnormalities and Severity in Neonate with NEC
- Affiliations
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- 1Department of Pediatrics, Pochon CHA University, College of Medicine, Sungnam, Korea. khlee45@yahoo.co.kr
- 2Department of Radiology, Pochon CHA University, College of Medicine, Sungnam, Korea.
- 3Department of Preventive Medicine, Pochon CHA University, College of Medicine, Sungnam, Korea.
Abstract
OBJECTIVES
The purpose of this study is to evaluate the association between hematologic abnormalities and severity in neonate with NEC.
METHODS
A retrospective chart review was established of 69 premature infants with a diagnosis of NEC who had been admitted to Pochon CHA University neonatal intensive care unit between Jan 2001 and Jun 2004. Infants were divided into three groups according to Bell's criteria. The association between perinatal and clinical manifestation, hematologic abnormalities and severity in neonate with NEC was evaluated.
RESULTS
Nadir platelet counts, neutropenia, I:T ratio, CRP and base excess were associated with severity of NEC, but coagulation disturbances (DIC) were not significantly correlated with severity of NEC.
CONCLUSION
These preliminary results may be helpful to predict the severity and to improve the outcome in neonate with NEC.
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