J Korean Surg Soc.  2011 Jul;81(1):19-24. 10.4174/jkss.2011.81.1.19.

Clinicopathologic characteristics of serosa-positive gastric carcinoma in elderly patients

• Kim HG
• Kang H
• Kim DY
• Joo JK
• Ryu SY
• Lee JH

• KMID: 1853527
• DOI: http://doi.org/10.4174/jkss.2011.81.1.19

Abstract

PURPOSE
The relationship between the prognosis and the age of patients with gastric carcinoma is controversial. This study examined the clinicopathologic features of elderly gastric carcinoma patients with serosal invasion.
METHODS
We reviewed the hospital records of 136 elderly gastric carcinoma patients with serosal invasion retrospectively to compare the clinicopathologic findings in the elderly (aged > 70 years) and young (aged < 36 years).
RESULTS
The 5-year survival rates of elderly and young patients with curative resection did not differ statistically (33.9% vs. 43.3%; P = 0.318). Multivariate analysis showed that two factors were independent, statistically significant parameters associated with survival: histologic type (risk ratio, 1.805; 95% confidence interval [CI], 1.041 to 3.132; P < 0.05) and operative curability (risk ratio, 2.506; 95% CI, 1.371 to 4.581; P < 0.01).
CONCLUSION
This study demonstrated that elderly gastric carcinoma patients with serosal invasion do not have a worse prognosis than young patients. The important prognostic factor was whether the patients underwent curative resection.

Keyword

Gastric carcinoma; Serosal invasion; Elderly; Prognosis; Age

MeSH Terms

Aged
Hospital Records
Humans
Multivariate Analysis
Prognosis
Retrospective Studies
Survival Rate

Figure

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  Fig. 1 Survival curves of the young and elderly groups. The 5-year survival rates of young and elderly patients did not differ statistically.

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  Fig. 2 Survival curves of the young and elderly groups with serosal invasion; curative resection patients.

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  Fig. 3 Survival curves of elderly patients according to resectability. Survival curves of elderly patients with curative resection had better than those of patients with non-curative resection.

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