J Korean Radiol Soc.  2002 Feb;46(2):133-139. 10.3348/jkrs.2002.46.2.133.

Recurrent Pyogenic Cholangitis: Clinico-Pathologic Correlation of Focal Attenuation Differences on Multi-Phasic Spiral CT

• Jeong JY
• Han JK
• Kim TK
• Kim SJ
• Kim HB
• Choi BI

• KMID: 1832976
• DOI: http://doi.org/10.3348/jkrs.2002.46.2.133

Abstract

PURPOSE
To determine the clinical and the pathologic significance of the focal attenuation differences (FAD) and bile duct wall enhancement occurring in recurrent pyogenic cholangitis (RPC) and seen at multiphasic spiral CT.
MATERIALS AND METHODS
Among the multiphasic (non-contrast, arterial and portal or delayed phase) spiral CT findings of 60 consecutive patients, two types of FAD were noted during the non-contrast phase. These were Type A (iso) and Type B (low attenuation), and their distribution pattern (lobar versus patchy, multifocal) and the and the presence or absence of bile duct wall enhancement were recorded. The radiologic findings were correlated with the clinical and pathologic findings.
RESULTS
Two types of FAD were noted in 40 of the 60 patients. Active in flammation was present in 19 of the 27 with Type-A and in ten of the 15 in whom the presence of RPC was pathologically proven. Ten of the 13 with Type-B FAD were in a subclinical state, and nine of the ten in whom RPC was pathologically proven had chronic inflammation. Among 20 patients who did not have FAD, RPC was subclinical in 18 and dormant in nine of the eleven in whom its presence was pathologically proven (p<0.001). Clinico-pathologic correlation with bile duct wall enhancement and the distribution pattern of FAD showed no statistical significance.
CONCLUSION
The inflammatory activity of RPC can be predicted by analysis of the FAD seen at multiphasic spiral CT.

Keyword

Cholangitis; Bile ducts, calculi; Bile ducts, CT

MeSH Terms

Bile Ducts
Cholangitis*
Flavin-Adenine Dinucleotide
Humans
Inflammation
Tomography, Spiral Computed*
Flavin-Adenine Dinucleotide