Genomics Inform.
2013 Mar;11(1):52-54. 10.5808/GI.2013.11.1.52.
Eukaryotic DNAJ/K Database: A Comprehensive Phylogenomic Analysis Platform for the DNAJ/K Family
- Affiliations
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- 1Fungal Bioinformatics Laboratory, Seoul National University, Seoul 151-921, Korea. yonglee@snu.ac.kr
- 2Department of Agricultural Biotechnology, Seoul National University, Seoul 151-921, Korea.
- 3Center for Fungal Pathogenesis, Seoul National University, Seoul 151-921, Korea.
- 4Center for Fungal Genetic Resources, Seoul National University, Seoul 151-921, Korea.
- KMID: 1806271
- DOI: http://doi.org/10.5808/GI.2013.11.1.52
Abstract
- Proteins in DNAJ/K families are ubiquitous, from prokaryotes to eukaryotes, and function as molecular chaperones. For systematic phylogenomics of the DNAJ/K families, we developed the Eukaryotic DNAJ/K Database (EDD). A total of 12,908 DNAJs and 4,886 DNAKs were identified from 339 eukaryotic genomes in the EDD. Kingdom-wide comparison of DNAJ/K families provides new insights on the evolutionary relationship within these families. Empowered by 'class', 'cluster', and 'taxonomy' browsers and the 'favorite' function, the EDD provides a versatile platform for comparative genomic analyses of DNAJ/K families.
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