Pediatr Infect Vaccine.  2015 Apr;22(1):36-39. 10.14776/piv.2015.22.1.36.

A Case of Childhood Typhoid Fever Complicated with Acute Nephritis

• Oh EM
• Sim JH
• Hwang JH
• Yim HE
• Kim YK

• KMID: 1791515
• DOI: http://doi.org/10.14776/piv.2015.22.1.36

Abstract

Typhoid fever can cause serious complications, such as enterobrosia, meningitis, pneumonia, myocarditis, hepatitis, osteomyelitis, and disseminated intravascular coagulation in 10-15% of the patients. Kidney complications are very rare, and a few cases have been reported in children. We are reporting a case of childhood typhoid fever complicated with acute nephritis present with albuminuria, hypertension, and renal failure.

Keyword

Typhoid fever; Nephritis; Renal failure

MeSH Terms

Albuminuria
Child
Disseminated Intravascular Coagulation
Hepatitis
Humans
Hypertension
Kidney
Meningitis
Myocarditis
Nephritis*
Osteomyelitis
Pneumonia
Renal Insufficiency
Typhoid Fever*

Figure

• 

  Fig. 1. 1. Abdominal CT. Wall thickening of cecum and terminal ileum were found in abdominal CT, and mesenteric and left para-aortic lymphadenopathy were found also.

• 

  Fig. 2. Abdominal sono. Diffused enlargement was found in both kidneys and there were increased cortical echogenicity in the kidneys.

Reference

1. Lee IK. Summary of communicable disease outbreak during thirty fifth week in 2007. Communicable disease weekly report. 2007. 6z1–35.

2. Zulfigar AB. Enteric fever. In:. Kliegman RM, Stanton BF, St. Geme IW, Schor NF, Behrman RE, editors. Nelson Textbook of Pediatrics. 19th ed.Philadelphia: WB Sounders C0;2011. p. 955.

3. Qutaishat SS, Stemper ME, Spencer SK, Borchardt MA, Opitz IC, Monson TA, et al. Transmission of Salmonella enterica serotype typhimurium DT 104 to infants through mother's breast milk. Pediatrics. 2003; 6:1442–6.

4. Park IK, Seok WW, Choi B], Kim HM, Lim BK, Yoon SS, et al. Salmonella enterica serovar London infections associated with consumption of infant formula. Yonsei Med I. 2004; 45:43–8.

5. Lim HS. Contributing factors of infectious waterborne and foodborne outbreaks in Korea. I Korean Med Assoc. 2007; 50:582–91.

6. Lim HS, Min YS, Lee K, Lim SH. Epidemiologic investigation into an outbreak of typhoid fever recognized by electronic data interchange in gyeongsanbuk—do, 2003. Korean I Epidemiol. 2004; 26:59–68.

7. Shin SY, Hong JY, Bae IM. An Epidemic survey for salmonellosis occurred on a baby's first birthday banquet in Ieju Island. Korean J Epidemiol. 2004; 26:27–38.

8. Parry CM, Hien TT, Dougan G, White N], Farrar I]. Typhoid fever. N Engl J Med. 2002; 347:1770–82.

9. Ianssen van Doorn K, Pierard D, Verbeelen D. Typhoid fever. N Engl I Med. 2003; 20:1182–4.

10. Hayashi M, Kouzu H, Nishihara M, Takahashi T, Furuhashi M, Sakamoto K, et al. Acute renal failure likely due to acute nephritis syndrome associated with typhoid fever. Intern Med. 2005; 44:1074–7.

11. Sreedharan R, Avnar ED. Acute renal failure. In:. Kliegman RM, Stanton BF, St. Geme, Schor NF, Behrman RE, editors. Nelson Textbook of Pediatrics. 19th ed.Philadelphia: WB Sounders Co;2011. p. 1818.

12. Sitprija V, Pipatanagul V, Boonpucknavig V, Boonpucknavig S. Glomerulitis in typhoid fever, Ann Intern Med. 1974; 81:210–3.

13. Oh 1M, Lee NR, Yim HE, Yoo KH, Ieong WY, Hong YS, et a1. Acute tubulointerstitial nephritis With renal failure complicated by typhoid fever, J Korean Soc Pediatr Nephrol. 2010; 14:236–9.

14. Buysen IG, Houthoff H], Kredjet RT, Arisz L. Acute interstitial nephritis: a clinical and morphological study in 27 patients. Nephrol Dial Transplant. 1990. 5294–9.

15. Shin P]. Lee HS, Cho BS, Ahn CI, Yang MH. Acute tubular necrosis associated with typhoid fever, Korean I Pediatr. 1994; 37:250–6.

16. Murithi AK, Leung N, Valeri AM, Cornell LD, Sethi S, Fidler ME et a1. Biopsy—proven acute interstitial nephritis, 1993—2011: A case series, Am I Kidney Dis. 2014; 64:558–66.