Yonsei Med J.  2008 Dec;49(6):931-941. 10.3349/ymj.2008.49.6.931.

Estimated Prevalence and Risk Factor for Age-related Maculopathy

• Roh MI
• Kim JH
• Byeon SH
• Koh HJ
• Lee SC
• Kwon OW

• KMID: 1782941
• DOI: http://doi.org/10.3349/ymj.2008.49.6.931

Abstract

PURPOSE
To assess the estimate prevalence and risk factors for age-related maculopathy (ARM) in Seoul, Korea. PATIENTS AND METHODS: We examined 9,530 subjects with, 40 years of age or older between January 2006 and December 2006 in Seoul, Korea. Subjects underwent fundus photography, clinical examinations (including blood analyses), and completed detailed questionnaires. Fundus images were graded according to definitions from the Wisconsin Age-Related Maculopathy Grading System. RESULTS: ARM was present in 235 subjects, corresponding to an estimate prevalence of 2.46%. Hepatitis B infection (positive status for HBsAg and HBcAb), serum triglyceride levels and high density lipoprotein levels remained as significant risk factors after age-adjustment. Multivariate analyses showed that the prevalence of ARM was significantly higher in older subjects [odds ratio (OR) 1.134; 95% CI 1.114-1.154] and those who were seropositive for hepatitis B surface antigen (OR 2.566; 95% CI 1.519-4.335). CONCLUSION: The estimated prevalence of ARM was 2.46%. Age and hepatitis B infection may increase the risk of ARM.

Keyword

Age-related maculopathy; hepatitis B; triglyceride; high-density lipoprotein

MeSH Terms

Adult
Age Factors
Aged
Female
Hepatitis B/complications
Humans
Korea/epidemiology
Lipoproteins, HDL/blood
Macular Degeneration/blood/*epidemiology/etiology
Male
Middle Aged
Risk Factors
Triglycerides/blood

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