Yonsei Med J.  2006 Aug;47(4):575-577. 10.3349/ymj.2006.47.4.575.

Invasive Papillary Carcinoma of the Breast Presenting as Post-Traumatic Recurrent Hemorrhagic Cysts

Affiliations
  • 1Department of Diagnosic Radiology, Pocheon CHA University College of Medicine, Gyeonggi, Korea.
  • 2Department of Diagnostic Radiology, Research Institute of Radiological Science, Yonsei University College of Medicine, Seoul, Korea. ekkim@yumc.yonsei.ac.kr
  • 3Department of Surgery, Yonsei University College of Medicine, Seoul, Korea.

Abstract

We report the sonographic features of an intracystic papillary carcinoma of the breast presenting as recurrent hemorrhagic cysts following trauma. A 56-year-old woman presented with palpable breast masses after a traumatic event; sonography showed multiple, well-defined, hemorrhagic cysts. Hemorrhagic fluid was evacuated by fine needle aspiration with no residual lesions. Cytology was negative for malignancy. Five months later, the mass reappeared; sonography demonstrated multiple cysts with solid nodules. US-guided core biopsy and surgery revealed invasive papillary carcinoma. We suggest close follow-up of cystic masses, even with negative cytology, and performance of surgical excisional biopsy in cases of rapid refilling after aspiration.

Keyword

Breast neoplasms; diagnosis; breast; ultrasonogram; breast; cysts

MeSH Terms

Ultrasonography, Mammary/methods
Recurrence
Middle Aged
Mammography/methods
Lymphatic Metastasis
Humans
Hemorrhage/*diagnosis/ultrasonography
Female
Diagnosis, Differential
Cysts/*diagnosis/ultrasonography
Carcinoma, Papillary/*diagnosis/ultrasonography
Breast Neoplasms/*diagnosis/ultrasonography

Figure

  • Fig. 1 (A) Mammogram. Both mediolateral oblique (a) and craniocaudal mammogram (b) showed multiple round shape masses with well-defined margins in the subareolar area and upper outer quadrant of the right breast. (B) Ultrasonogram. The initial sonogram shows well-circumscribed cystic masses with echogenic floating debris (arrows) at the subareolar (a) and upper outer quadrant (b) of the right breast. Sonograms obtained at 5 month follow up. Cystic mass size was markedly increased, with irregular shaped soft tissue (arrows) along the cyst walls (c). The blood flow signals of the papillary solid portion are shown on color Doppler sonography (d).


Cited by  2 articles

Clinicopathological Characteristics of Male Breast Cancer
Seho Park, Joo-Hee Kim, Jaseung Koo, Byeong-Woo Park, Kyong Sik Lee
Yonsei Med J. 2008;49(6):978-986.    doi: 10.3349/ymj.2008.49.6.978.

Experience with Intracystic Papillary Carcinoma of the Breast at a Single Institute in Korea
Se Kyung Lee, Jae Hyuck Choi, Hye In Lim, Wan Wook Kim, Sangmin Kim, Eun Yoon Cho, Jun-Ho Choe, Jung-Han Kim, Jee Soo Kim, Seok-Jin Nam, Jung-Hyun Yang, Jeong Eon Lee
J Breast Cancer. 2009;12(4):338-343.    doi: 10.4048/jbc.2009.12.4.338.


Reference

1. Framarino dei Malatesta ML, Piccioni MG, Felici A, Paolucci A, Triglia A, Galati G, et al. Intracystic carcinoma of the breast. Our experience. Eur J Gynaecol Oncol. 1992. 13(1):Suppl. 40–44.
2. Hamed H, Coady A, Chaudary MA, Fentiman IS. Follow-up of patients with aspirated breast cysts is necessary. Arch Surg. 1989. 124:253–255.
3. Liberman L, Feng TL, Susnik B. Case 35: Intracystic papillary carcinoma with invasion. Radiology. 2001. 219:781–784.
4. Soo MS, Williford ME, Walsh R, Bentley RC, Kornguth PJ. Papillary carcinoma of the breast: imaging findings. AJR. 1995. 164:321–326.
5. Liston JC. Case report: an unusual interval breast cancer masquerading as a simple cyst. Clin Radiol. 1997. 52:876–878.
6. Cowen PN, Benson EA. Cytological study of fluid from breast cysts. Br J Surg. 1979. 66:209–211.
7. Devitt JE, Barr JR. The clinical recognition of cystic carcinoma of the breast. Surg Gynecol Obstet. 1984. 159:130–132.
8. Corkill ME, Sneige N, Fanning T, el-Naggar A. Fine-needle aspiration cytology and flow cytometry of intracystic papillary carcinoma of breast. Am J Clin Pathol. 1990. 94:673–680.
9. Markopoulos C, Kouskos E, Gogas H, Kakisis J, Kyriakou V, Gogas J, et al. Diagnosis and treatment of intracystic breast carcinomas. Am Surg. 2002. 68:783–786.
10. Solorzano CC, Middleton LP, Hunt KK, Mirza N, Meric F, Kuerer HM, et al. Treatment and outcome of patients with intracystic papillary carcinoma of the breast. Am J Surg. 2002. 184:364–368.
11. Dogan BE, Whitman GJ, Middleton LP, Phelps M. Intracystic papillary carcinoma of the breast. Am J Roentgenol. 2003. 181:186.
12. Matsuo S, Eto T, Soejima H, Ohara O, Hidaka O, Miyazaki J, et al. A case of intracystic carcinoma of the breast: the importance of measuring carcinoembryonic antigen in aspirated cystic fluid. Breast Cancer Res Treat. 1993. 28:41–44.
Full Text Links
  • YMJ
Actions
Cited
CITED
export Copy
Close
Share
  • Twitter
  • Facebook
Similar articles
Copyright © 2024 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr