Korean J Gastroenterol.  2010 Jan;55(1):1-3. 10.4166/kjg.2010.55.1.1.

A Case of Malignant Melanoma Metastasized to Liver and Gastrointestinal Tract

• Lee KN
• Lee OY

• KMID: 1775920
• DOI: http://doi.org/10.4166/kjg.2010.55.1.1

Abstract

No abstract available.

MeSH Terms

Aged
Female
Gastrointestinal Neoplasms/*diagnosis/pathology/*secondary
Humans
Liver Neoplasms/*diagnosis/radiography/*secondary
Melanoma/*pathology
Skin Neoplasms/*pathology
Tomography, X-Ray Computed

Figure

• 

  Fig. 1. (A) Endoscopic findings. Multiple melanotic nodules were scattered on the mucosal surfaces of lower and mid body of the stomach. (B) Slightly depressed mucosae with a pigmented base were seen in the bulb of the duodenum.

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  Fig. 2. Abdominal CT scan with oral and intravenous contrast. Multiple hypodense target-like lesions were scattered throughout the entire liver.

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  Fig. 3. (A) Pathologic findings. Malignant melanoma cells infiltrated the lamina propria of the stomach in a nesting fashion (H&E stain, ×400). (B) Pathologic findings. Cells infiltrated in the lamina propria of gastric mucosa showed a stong positive immunohistochemical stains for S-100 protein suggesting a metastatic malignant melanoma (S-100 IHC stain, ×400). (C) Pathologic findings. HMB immunohistochemical stains demonstrated metastatic malignant melanoma cells scattered around the glandular structures of gastric mucosa (HMB-45 IHC stain, ×400).

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