Korean J Gastroenterol.  2013 Feb;61(2):110-113. 10.4166/kjg.2013.61.2.110.

Multiple Neuroendocrine Tumor of the Distal Ileum

Affiliations
  • 1Department of Internal Medicine, Dong-A University School of Medicine, Busan, Korea. jh2002@dau.ac.kr

Abstract

No abstract available.


MeSH Terms

Antigens, CD56/metabolism
Capsule Endoscopy
Humans
Ileal Neoplasms/*diagnosis/pathology/radiography
Ki-67 Antigen/metabolism
Lymph Nodes/radiography
Male
Middle Aged
Neoplasm Staging
Neuroendocrine Tumors/*diagnosis/pathology/radiography
Positron-Emission Tomography and Computed Tomography
Tomography, X-Ray Computed
Antigens, CD56
Ki-67 Antigen

Figure

  • Fig. 1. Abdominal CT showing homogeneously enhancing mass in the distal ileum with multiple lymph node enlargement, small bowel mesentery and mesenteric haziness (arrow).

  • Fig. 2. Capsule endoscopic finding. Luminal protruding masses were observed at the ileum.

  • Fig. 3. PET-CT showing hypermetabolic malignancy in the ileum with multiple regional lymph node metastasis in the small bowel mesentery (arrow).

  • Fig. 4. The small intestinal wall showed five nodular masses, measuring up to 4 × 3 cm in dimension (A), and each of masses had grayish fish-fresh like cut curface (B). (C) On microscope, the tumor was composed of uniform neuroendocrine cells with scant, lightly eosionphilic cytoplasm, arranged in nests and trabeculae (H&E, ×200). The tumor cells invaded through the muscularis propria into the subserosal tissue (inset). (D) The tumor cells showed intense cytoplasmic immunoreactivity with chromogranin A (×200).


Reference

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