Gut Liver.
2014 Mar;8(2):215-218.
Severe Bleeding and Perforation Are Rare Complications of Endoscopic Ultrasound-Guided Fine Needle Aspiration for Pancreatic Masses: An Analysis of 3,090 Patients from 212 Hospitals
- Affiliations
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- 1Department of Gastroenterology, The University of Tokyo Graduate School of Medicine, Tokyo, Japan. isayama-tky@umin.ac.jp
- 2Department of Health Economics and Epidemiology Research, The University of Tokyo School of Public Health, Tokyo, Japan.
- 3Department of Clinical Data Management and Research, Clinical Research Center, National Hospital Organization Headquarters, Tokyo, Japan.
- 4Department of Health Care Informatics, Tokyo Medical and Dental University, Tokyo, Japan.
- 5Department of Preventive Medicine and Community Health, University of Occupational and Environmental Health, Kitakyushu, Japan.
Abstract
- BACKGROUND/AIMS
Endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) is useful for the pathological diagnosis of pancreatic masses, but patients are susceptible to severe bleeding and perforation. Because the incidence and severity of these complications have not been fully evaluated.
METHODS
We aimed to evaluate severe bleeding and perforation after EUS-FNA for pancreatic masses using large-scale data derived from a Japanese nationwide administrative database.
RESULTS
In total, 3,090 consecutive patients from 212 low- to high-volume hospitals were analyzed. Severe bleeding requiring transfusion or endoscopic treatment occurred in seven patients (0.23%), and no perforation was observed. No patient mortality was recorded within 30 days of EUS-FNA. The rate of severe bleeding in low-volume hospitals was significantly higher than that in medium- and high-volume hospitals (0.48% vs 0.10%, p=0.045).
CONCLUSIONS
Severe bleeding and perforation following EUS-FNA for pancreatic masses are rare, and the procedure is safe.
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