Korean J Gastrointest Endosc.  2010 Sep;41(3):155-158.

A Case of Ectopic Sebaceous Glands in the Esophagus

  • 1Department of Internal Medicine, College of Medicine, Kwandong University, Goyang, Korea. chg21@kwandong.ac.kr
  • 2Department of Pathology, College of Medicine, Kwandong University, Goyang, Korea.


A 42-year-old man without any signs or symptoms of illness underwent esophagogastroduodenoscopy (EGD) for a routine health check up. On esophagogastroduodenoscopy, multiple small and yellowish mucosal plaques were detected in the mid to distal esophagus. These plagues proved to be ectopic sebaceous glands of the esophagus according to the histologic examination. On the immunohistochemical staining with anti-Keratin 14, the basal cells and the heterotopic sebaceous glands were immunoreactive for keratin 14. The histogenesis of this extremely rare lesion is not completely clear. There have been some reports on ectopic esophagus sebaceous glands combined with esophageal cancer or gastric cancer. However, malignant transformation of the ectopic sebaceous gland itself has not yet been reported on. This case was regularly followed up for 12 months, and no interval change or malignant transformation was found both endoscopically and histologically.


Ectopic; Sebaceous glands; Esophagus
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