Korean J Pain.  2010 Jun;23(2):147-150. 10.3344/kjp.2010.23.2.147.

Investigation of High-Sensitivity C-reactive Protein and Erythrocyte Sedimentation Rate in Low Back Pain Patients

• Park CH
• Lee SH

• KMID: 1770548
• DOI: http://doi.org/10.3344/kjp.2010.23.2.147

Abstract

BACKGROUND
Chronic low back pain can be a manifestation of lumbar degenerative disease, herniation of intervertebral discs, arthritis, or lumbar stenosis. When nerve roots are compromised, low back pain, with or without lower extremity involvement, may occur. Local inflammatory processes play an important role in patients with acute lumbosciatic pain. The purpose of this study was to assess the value of erythrocyte sedimentation rate (ESR) and high sensitivity C-reactive protein (hsCRP) measurements in patients with chronic low back pain or radiculopathy.
METHODS
ESR and hsCRP were measured in 273 blood samples from male and female subjects with low back pain and/or radiculopathy due to herniated lumbar disc, spinal stenosis, facet syndrome, and other diseases. The hsCRP and ESR were measured prior to lumbar epidural steroid injection.
RESULTS
The mean ESR was 18.8 mm/h and mean hsCRP was 1.1 mg/L. ESR had a correlation with age.
CONCLUSIONS
A significant systemic inflammatory reaction did not appear to arise in patients with chronic low back pain.

Keyword

ESR; hsCRP; low back pain

MeSH Terms

Arthritis
Blood Sedimentation
C-Reactive Protein
Constriction, Pathologic
Erythrocytes
Female
Humans
Intervertebral Disc
Low Back Pain
Lower Extremity
Male
Radiculopathy
Spinal Stenosis
C-Reactive Protein

Figure

• 

  Fig. 1 A positive correlation was found between erythrocyte sedimentation rate (ESR) levels and Ages (r = 0.332, P = 0.000).

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