Korean J Gastroenterol.  2008 Sep;52(3):179-182.

Ileal Mucormycosis Diagnosed by Colonoscopy in a Patient with Acute Myeloid Leukemia

Affiliations
  • 1Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea. geniushee@yuhs.ac
  • 2Department of Institute of Gastroenterology, Yonsei University College of Medicine, Seoul, Korea.
  • 3Department of Pathology, Yonsei University College of Medicine, Seoul, Korea.

Abstract

Gastrointestinal mucormycosis is an uncommon opportunistic fungal infection often presents in immunocompromised patients. Direct invasion of the intestinal walls by spores from ingested food is the main pathogenetic mechanism of this disease, which usually takes place in stomach and colon. Early diagnosis is critical, especially in vascular invasive types, due to its high mortality rate close to 100%. In the past when appropriate diagnostic tools were not available, mucormycosis were frequently found with autopsy. The advance in current endoscopic technology has increased diagnostic rate and made successful management available with appropriate treatments such as debridement of contaminated tissues. In this case report, we discussed a case of ileal mucormycosis diagnosed by colonoscopy and treated with anti-fungal agent successfully.

Keyword

Mucormycosis; Colonoscopy; Leukemia, Myeloid, Acute

MeSH Terms

Amphotericin B/therapeutic use
Antifungal Agents/therapeutic use
Colonoscopy
Humans
Ileal Diseases/*diagnosis/microbiology/therapy
Ileum/pathology
Immunocompromised Host
Leukemia, Myeloid, Acute/*complications/drug therapy
Male
Mucormycosis/*diagnosis/etiology/therapy
Tomography, X-Ray Computed
Young Adult
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