Korean J Dermatol.  2004 Jan;42(1):65-68.

A Case of Congenital Melanocytic Nevus Undergoing Regression in Association with Vitiligo

• Choi HJ
• Ku JK
• Park YM
• Kim HO

Abstract

Congenital melanocytic nevi rarely develop depigmentation, and only a few cases have been reported in the literature. We, herein, present a case of congenital melanocytic nevus which has undergone progressive involution in association with vitiligo. A 23-year-old man had a dark brownish patch partially surrounded by the depigmented patch on his mid back. He also had multiple depigmented patches on his trunk and neck, which had developed since the age of 5. Histopathologic examination from the dark brownish patch adjacent to the depigmented area showed typical findings of compound nevus with a mild perivascular lymphocytic infiltration. TUNEL staining from the same lesion demonstrated many strong positive epidermal basal cells as well as dermal nevus cells, indicative of apoptosis.

Keyword

Congenital melanocytic nevus; Vitiligo; Regression; Apoptosis

MeSH Terms

Male
Humans