Korean J Pathol.
2001 Aug;35(4):354-356.
A Case of Solitary Cutaneous Myofibroma of the Thigh in An Adult
- Affiliations
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- 1Departments of Pathology, College of Medicine, Hanyang University, Seoul 133-792, Korea; Department of Anatomical Pathology, Inha University Hospital, Inchon 400-103, Korea. parkmh@hanyang.ac.kr
- 2Departments of Dermatology, College of Medicine, Hanyang University, Seoul 133-792, Korea; Department of Anatomical Pathology, Inha University Hospital, Inchon 400-103, Korea. parkmh@hanyang.ac.kr
Abstract
- Adult solitary cutaneous myofibroma is a recently described benign neoplasm of the skin or subcutis, representing the adult counterpart of infantile myofibroblastoma. The histologic and immunohistochemical features of a 21-year-old woman with a solitary brownish, mildly tender nodule on her right thigh are reported here. The nodule had been present for a duration of 3 years. It showed a nodular dermal mass with an irregular margin. The lesion consisted of interlacing bundles of spindle cells which were positive for smooth muscle actin, muscle specific actin and vimentin. Immunohistochemical stainings for desmin, S-100 protein, CD 34 and CD 68 were negative. Cutaneous myofibroma in an adult is a distinct entity of benign neoplasm.
