Korean J Pathol.  1995 Sep;29(4):521-523.

Coexisting Adenocarcinoma and Epithelioid Leiomyosarcoma of Stomach: A case report

  • 1Department of Anatomic Pathology, Korea Cancer Center Hospital, Seoul, Korea.
  • 2Department of Pathology, Seoul National University College of Medicine, Seoul, Korea.


We report a case of malignant tumor of the stomach showing both carcinoma and sarcoma components in a 47 year-old woman. The resected stomach revealed two tumors which were in different location. The one mass was a 2 x I cm, poorly demarcated tumor at the body, along the lesser curvature and the other was a 6 x 7 cm, well demarcated polypoid tumor with a central depression at cardia of the posterior stomach wall. The tumor at the body was a poorly differentiated adenocarcinoma which showed strong reactivity for CEA. The tumor at the cardia was composed of epithelioid or spindle shaped cells with abundant eosinophilic cytoplasm and revealed 5-6 mitoses per ten high power field. The tumor at the cardia was diagnosed as epithelioid leiomyosarcoma and showed reactivity for vimentin but none for actin, desmin,keratin, and CEA. This is different from the usual carcinosarcoma.


Adenocarcinoma; Epithelioid leiomyosarcoma; Carcinosarcoma; Stomach

MeSH Terms

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