Korean J Gastroenterol.  2011 Apr;57(4):230-236. 10.4166/kjg.2011.57.4.230.

Follow-up Results of Endoscopic Mucosal Resection for Early Colorectal Cancer

• Lee HJ
• Jeong HY
• Park NH
• Hong SC
• Nam GW
• Moon HS
• Lee ES
• Kim SH
• Sung JK
• Lee BS

• KMID: 1718403
• DOI: http://doi.org/10.4166/kjg.2011.57.4.230

Abstract

BACKGROUND/AIMS
Recently colonoscopy and screening programs have led to the detection and removal of increasing numbers of early colorectal cancer (ECC), which can reduce its related mortality. We analysed the clinical, endoscopic, and histologic findings, as well as the follow-up data, to evaluate the effectiveness and the long-term results of endoscopic mucosal resection (EMR) for ECC.
METHODS
We analysed, retrospectively, 94 lesions in 92 patients who underwent EMR for ECC from January 2002 to June 2009.
RESULTS
The overage age of patients was 60 years old. The mean follow-up period was 22.1 months (6-80). En bloc resection rate was 64.9%. Submucosal invasion was found in 30 cases (31.9%). De novo cancer rate was 26.6% which had higher submucosal invasion rate (60%, p=0.003). The complete resection rate was 87.2%, and there was no recurrence of cancer during follow-up (p=0.000). Twelve incomplete resection cases had received further surgical treatments. No procedure-related mortality was found and no recurrent malignancy was found except 1 case.
CONCLUSIONS
This study shows that EMR is an effective and safe treatment for ECC. En bloc resection provides precise histologic information and prevention of tumor recurrence.

Keyword

Early colorectal cancer; Colonoscopy; Mucosal resection

MeSH Terms

Adenoma/pathology/surgery
Adult
Aged
Aged, 80 and over
Colorectal Neoplasms/*epidemiology/pathology/surgery
Endoscopy, Gastrointestinal
Female
Follow-Up Studies
Humans
Intestinal Mucosa/*surgery
Male
Middle Aged
Neoplasm Invasiveness
Recurrence
Retrospective Studies

Reference

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