Korean J Intern Med.  2009 Jun;24(2):147-152. 10.3904/kjim.2009.24.2.147.

A Case of Hepatocellular Carcinoma Within Hepatocellular Adenoma in a Non-Cirrhotic Male

Affiliations
  • 1Department of Internal Medicine, National Health Insurance Corporation Ilsan Hospital, Goyang, Korea.
  • 2Department of Pathology, National Health Insurance Corporation Ilsan Hospital, Goyang, Korea.
  • 3Department of Diagnostic Radiology, National Health Insurance Corporation Ilsan Hospital, Goyang, Korea.
  • 4Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea.
  • 5Institute of Gastroenterology, Yonsei University College of Medicine, Seoul, Korea. dyk1025@yuhs.ac

Abstract

Hepatocellular adenoma (HA) is a benign hepatic lesion that predominantly occurs in young women. Most hepatocellular carcinomas (HCC) arise in a cirrhotic liver during the fifth or sixth decades. There have been several reported cases of HCC developing from HA in female patients. However, there are rare cases about HCC arising in HA in a non-cirrhotic male patient. We have recently encountered a 53-year-old man who had a liver mass in a non-cirrhotic liver, and the liver mass was compatible with HA on the pre-operative computed tomography. The mass was completely resected and the histopathology revealed a focus of HCC arising in HA. We report here on this case along with a brief review of the relevant literature

Keyword

Adenoma; Hepatocellular; Hepatocellular carcinoma

MeSH Terms

Adenoma, Liver Cell/*pathology/surgery
Adult
Biopsy
Carcinoma, Hepatocellular/*pathology/surgery
Female
Hepatectomy
Humans
Liver Neoplasms/*pathology/surgery
Male
Middle Aged
Precancerous Conditions/*pathology/surgery
Tomography, X-Ray Computed
Treatment Outcome
Ultrasonography
Young Adult
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