Yonsei Med J.  2012 Jul;53(4):753-758. 10.3349/ymj.2012.53.4.753.

Clinical Features of Fitz-Hugh-Curtis Syndrome in the Emergency Department

• You JS
• Kim MJ
• Chung HS
• Chung YE
• Park I
• Chung SP
• Kim S
• Lee HS

• KMID: 1716874
• DOI: http://doi.org/10.3349/ymj.2012.53.4.753

Abstract

PURPOSE
Fitz-Hugh-Curtis Syndrome (FHCS) is a clinical entity characterized by inflammation of the liver capsule associated with genital tract infection. The aim of this study is to provide physicians with clinical suggestions for diagnostic approaches based on a series of patients who were diagnosed with FHCS.
MATERIALS AND METHODS
We conducted a retrospective study of patients who were diagnosed with FHCS after presenting to the emergency department (ED). The symptoms, physical examinations, laboratory findings, radiological findings, and progress of the patients were reviewed.
RESULTS
During the four-year study period, a total of 82 female patients received a final diagnosis of FHCS in the ED. Chlamydia trachomatis was identified as a pathogen in 89% of the patients. Their clinical characteristics and laboratory findings were described. Fifty-two patients (63.4%) were admitted to the hospital. All of the admitted patients improved after treatment combining antibiotic therapy with conservative care.
CONCLUSION
FHCS should be considered as a differential diagnosis for female patients of childbearing age with right upper abdominal pain. Timely diagnosis using biphasic computed tomography (CT) with arterial and portal phases may help ensure adequate medical treatment as well as avoid invasive procedures.

Keyword

Pelvic inflammatory disease; abdominal pain; computed tomography

MeSH Terms

Adolescent
Adult
Anti-Bacterial Agents/therapeutic use
Chlamydia Infections/drug therapy/microbiology/*pathology/radiography
Chlamydia trachomatis/pathogenicity
Emergency Service, Hospital
Female
Hepatitis/drug therapy/microbiology/*pathology/radiography
Humans
Pelvic Inflammatory Disease/drug therapy/microbiology/*pathology/radiography
Peritonitis/drug therapy/microbiology/*pathology/radiography
Reproductive Tract Infections/drug therapy/microbiology/pathology/radiography
Retrospective Studies
Tomography, X-Ray Computed
Young Adult

Figure

• 

  Fig. 1 Arterial phase scans revealed increased perihepatic enhancement (arrowheads) on the right and left lobes of the liver in this patient.

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