J Korean Acad Nurs.  2013 Dec;43(6):801-811. 10.4040/jkan.2013.43.6.801.

Changes in Quality of Life and Related Factors in Thyroid Cancer Patients with Radioactive Iodine Remnant Ablation

Affiliations
  • 1Nuclear Medicine Department, Asan Medical Center, Seoul, Korea.
  • 2College of Nursing, Research Institute of Nursing Science, Seoul National University, Seoul, Korea. smi@snu.ak.kr

Abstract

PURPOSE
To investigate changes in Quality of life (QOL) and related factors in patients with thyroid cancer undergoing Radioactive Iodine remnant ablation (RAI).
METHODS
Data were collected longitudinally 3 times for 6 months (2 weeks post-surgery, post RAI, 3 months post RAI) in a hospital located in Seoul. Questionnaires were used to measure levels of physical symptoms, anxiety, depression, and QOL. Ninety-eight patients with thyroid cancer who had RAI were included in the analysis. Data were analyzed using SPSS (18.0).
RESULTS
Findings for the three data collection times respectfully were: mean scores for physical symptoms, 0.53, 1.21 and 0.62, patients with depression, 47%, 36.7% and 37.7%, patients with anxiety, 18.4%, 19.4% and 20.4%, mean scores for QOL, 7.06, 7.01 and 7.28. QOL score was highest 3 months post RAI (p=.031). In the stepwise multiple regression analysis, depression and fatigue were predicting factors for low QOL at all data collection times. Dysponia was a predicting factor for low QOL post RAI and 3 months post RAI.
CONCLUSION
To increase QOL, it is necessary to provide information in advance regarding physical & psychological symptoms and to develop nursing intervention programs to decrease depression and fatigue.

Keyword

Thyroid cancer; Radioactive iodine remnant ablation; Quality of life

MeSH Terms

Adult
Anxiety
Depression
Fatigue
Female
Humans
Iodine Radioisotopes/therapeutic use
Male
Middle Aged
*Quality of Life
Questionnaires
Radiopharmaceuticals/*therapeutic use
Regression Analysis
Thyroid Neoplasms/drug therapy/*radiotherapy/surgery
Time Factors
Iodine Radioisotopes
Radiopharmaceuticals

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