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Current Guidelines for Management of Medullary Thyroid Carcinoma

Kim M, Kim BH

Medullary thyroid carcinoma (MTC) is a rare neuroendocrine tumor originating from the parafollicular cells. The diagnostic and therapeutic strategies for the condition are different from those used for well-differentiated thyroid...
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Evaluation of Iodine Status among Korean Patients with Papillary Thyroid Cancer Using Dietary and Urinary Iodine

Choi JY, Lee JH, Song Y

Background: Concerns have been raised regarding thyroid disorders caused by excessive iodine in Koreans, who have iodine-rich diets. This study evaluated iodine status using dietary iodine intake and urinary iodine...
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The Changes in the Trend of Thyroid Cancer incidence for Korean Population: Consecutive 10 Years Analysis (2004-2013)

Lee JS, Kang SW, Lim CY

Background/Objectives: To analyze changes in the incidence of thyroid cancer for Korean population using big data from the National Health Insurance Service. Materials & Methods: Sample cohort database between January 2004...
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Clinicopathological Features of Patients Diagnosed with Both Primary Thyroid Cancer and Primary Renal Cell Cancer and Its Comparison with Patients with Thyroid Cancer or Renal Cell Cancer Alone

Park J, Kim YN, Ryoo H, Park H, Park SY, Kim TH, Chung JH, Seo SI, Kim SW

Background and Objectives: Thyroid cancer (TC) and renal cell carcinoma (RCC) display more frequent co-occurrence than would be expected by chance. We investigated clinicopathological features of patients with both primary...
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Protocol for a Korean Multicenter Prospective Cohort Study of Active Surveillance or Surgery (KoMPASS) in Papillary Thyroid Microcarcinoma

Jeon MJ, Kang YE, Moon JH, Lim DJ, Lee CY, Lee YS, Kim SW, Kim MH, Kim BH, Kang HC, Shong M, Cho SW, Kim WB

Background: A Korean Multicenter Prospective cohort study of Active Surveillance or Surgery (KoMPASS) for papillary thyroid microcarcinomas (PTMCs) has been initiated. The aim is to compare clinical outcomes between active...
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Clinical practice guidelines for radiofrequency ablation of benign thyroid nodules: a systematic review

Lee M, Baek JH, Suh CH, Chung SR, Choi YJ, Lee JH, Ha EJ, Na DG

Purpose: Thermal ablation is a novel treatment alternative for benign thyroid nodules, and one of the most promising thermal ablation techniques is radiofrequency ablation (RFA). Considering the increasing use of...
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Molecular Correlates and Nuclear Features of Encapsulated Follicular-Patterned Thyroid Neoplasms

Jung CK, Bychkov A, Song DE, Kim JH, Zhu Y, Liu Z, Keelawat S, Lai CR, Hirokawa M, Kameyama K, Kakudo K

Background: Assessing nuclear features is diagnostically challenging in the aspect of thyroid pathology. The aim of this study was to determine whether pathologists could distinguish BRAF-like and RAS-like nuclear features...
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Lactate Dehydrogenase A as a Potential New Biomarker for Thyroid Cancer

Ban EJ, Kim D, Kim JK, Kang SW, Lee J, Jeong JJ, Nam KH, Chung WY, Kim K

Background: Several cancers show increased levels of lactate dehydrogenase A (LDHA), which are associated with cancer progression. However, it remains unclear whether LDHA levels are associated with papillary thyroid cancer...
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The clinical meaning of pre- and post-ablation thyroglobulin levels at first radioiodine therapy in patients with papillary thyroid cancer

Kim HK, Yoon JH, Cho JS, Kwon SY, Yoo SW, Kang HC

Background/Aims: This study was conducted to identify prognostic factors in patients with papillary thyroid cancer (PTC) at the time of first radioactive iodine (RAI) therapy, and to evaluate the clinical...
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Deep Learning in Thyroid Ultrasonography to Predict Tumor Recurrence in Thyroid Cancers

Kil J, Kim KG, Kim YJ, Koo HR, Park JS

Purpose: To evaluate a deep learning model to predict recurrence of thyroid tumor using preoperative ultrasonography (US). Materials and Methods: We included representative images from 229 US-based patients (male:female = 42:187;...
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Expressions of miRNAs in Papillary Thyroid Carcinoma and Their Associations with the BRAFV600EMutation and Clinicopathological Features.

Yang SI, Choi YS

Objectives: The microRNAs (miRNAs) are known to be commonly expressed in papillary thyroid carcinoma. The BRAFV600Emutation is the most common genetic mutation in thyroid cancer. The main aim of this...
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Mechanisms of the Impact of Hashimoto Thyroiditis on Papillary Thyroid Carcinoma Progression: Relationship with the Tumor Immune Microenvironment

Sulaieva O, Chernenko S, Selesnov O, Nechay O, Maievskyi O, Falalyeyeva T, Kobyliak N, Tsyryuk O, Penchuk Y, Shapochka D

Background: The relationship between Hashimoto thyroiditis (HT) and papillary thyroid carcinoma (PTC) remains uncertain. We assessed the impact of HT on the tumor immune microenvironment (TIME) in PTC. Methods: Thirty patients...
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Development and Validation of a Risk Scoring System Derived from Meta-Analyses of Papillary Thyroid Cancer

Suh S, Goh TS, Kim YH, Oh SO, Pak K, Seok JW, Kim IJ

Background: The aim of this study was to develop a scoring system to stratify the risk of papillary thyroid cancer (PTC) and to select the proper management. Methods: We performed a...
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Coexistent Papillary Thyroid Carcinoma and Its Anaplastic Transformation in Cervical Lymph Node Metastasis

Song S, Lee DH, Kim H, Jeong WJ

The transformation of papillary thyroid carcinoma (PTC) to anaplastic thyroid carcinoma (ATC) is well documented in the literature but is an exceptionally rare occurrence in metastatic foci outside the primary...
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Thyroid Cancer Patients’ Interests and Information Seeking Behavior: Focused on Online Community Analysis

Park KA, Kim S, Lee YS, Chang HS, Park CS

Background and Objectives: Many patients with thyroid cancer are participating in the online community. Thyroid cancer patients write and read a variety of posts in the online community, and there...
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Computer-Aided Diagnosis System for the Evaluation of Thyroid Nodules on Ultrasonography: Prospective Non-Inferiority Study according to the Experience Level of Radiologists

Chung SR, Baek JH, Lee MK, Ahn Y, Choi YJ, Sung TY, Song DE, Kim TY, Lee JH

OBJECTIVE: To determine whether a computer-aided diagnosis (CAD) system for the evaluation of thyroid nodules is non-inferior to radiologists with different levels of experience. MATERIALS AND METHODS: Patients with thyroid nodules...
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A Case of a Temporary Endotracheal Stent for Airway Management in a Patient with Primary Thyroid Lymphoma

Kim YC, Yeo SC, Kim JP, Park JJ

Primary thyroid lymphoma is a rare malignancy that can grow rapidly and compress the airway. In such cases, a tracheostomy or thyroidectomy is generally required. Here, we report a case...
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The Effect of Saline Gargling on Dry Mouth and Sore Throat in Patients with Thyroidectomy

Kim DH, Park JS

Purpose: The purpose of this study was to investigate the effects of saline gargling on mouth dryness and sore throat for patients with thyroidectomy. Methods: A randomized controlled trial design...
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Perioperative Management of the Voice in Thyroid Cancer

Yoon SY, Hong HJ

Evaluating the patient’s voice before thyroidectomy is useful for the purpose of identifying patients with vocal cord paralysis without symptoms, identifying other patient’s voice abnormalities, and whether it is related...
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Thyroid Cancer Arising from Thyroglossal Duct Cyst

Kim HJ, Lee YS, Chang HS

Purpose: Thyroglossal duct cyst is the most common congenital anomaly of the neck, and malignancy arising from a thyroglossal duct cyst occurs only in approximately 1% of patients. Ultrasound examination and...
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