Korean J Dermatol.  1992 Apr;30(2):239-243.

A case of pretibial myxedema

Abstract

Pretibial myxedema, which consists of localized cutaneous accumulations of acid mucopolysaccharides, oceurs in a few patients with hyperthyroidi';m after its correction by surgery or radioactive iodine therapy. We report a case of pretibial myxedema with exophthalmos in a 36 year old male. He has suffered from hyperthyroidism with bilateral pretibial myxedema for a period of 4 years. He was treated with a subtotal thyroidectomy and excision of both pletibia lesions 1 year ago. The lesions recurred on t,he left pretibial area, as a 11 X 16cm sized, non pitting, non tender, swollen, brownish plaque. The histopathologic findings showed epidermal hyperkeratosis and a considerable arnount of mucin in the mid-dermis. We treat.ed him with intralesional injection of triamcinolone acetonide with marked improvement.

Keyword

Pretibial myxedema; Hyperthyroidism

MeSH Terms

Adult
Exophthalmos
Glycosaminoglycans
Humans
Hyperthyroidism
Injections, Intralesional
Iodine
Male
Mucins
Myxedema*
Thyroidectomy
Triamcinolone Acetonide
Glycosaminoglycans
Iodine
Mucins
Triamcinolone Acetonide
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