J Korean Neurol Assoc.
1993 Sep;11(3):467-470.
A Case of Steroid Myopathy in Istrogenic Cushing Syndrome
- Affiliations
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- 1Department of Neurology, College of Medicine, Hanyang University, Koea.
- 2Department of Internal Medicine, College of Medicine, Hanyang University, Koea.
- 3Department of Pathology, College of Medicine, Seoul National University, Korea.
Abstract
- Steroid myopathy is one of the most common drug-induced myopathy. We report a case of iatrogenic steroid myopathy in a 61-year-old female who had taken herb medication more than 2 months. She presented a slowly progressive proximal muscle weakness and wasting with typical features of cushing syndrome. Needle EMG showed typical myopathic patterns. The muscle biopsy revealed a pronounced muscle fiber atrophy and fatty degenerative change without inflammation. In addition, there was a selective type 2 fiber depletion on ATPase staining in pH 9.4 buffer. Her muscle powers and bulks were slowly improved after discontinuation of herb medication with phenytoin and physical therapy.
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