Korean J Dermatol.  1980 Oct;18(5):465-469.

A Case fo Toxic Epidermal Necrolysis

• Kwon OJ
• Suh JH
• Song JY

Abstract

A case of toxic epidermal necrolysis (TEN) was presented in 46 year-old male patient. The characteristic skin lesions of TEN were developed after some medictions and tetanus anti-toxin (TAT) injection due to trauma. Probably, the cause of the disease was drugs, TAT injection or trauma inself. On the pathologic findings, lower epidermis and dermo-epidermal cleavage were noticed. He was treated with massive antibiotics and steroid. About 7 days after therapy, much improvement achived. However foul odorous yellowish discharge was noticed since 20 days of hospitalization. Wide debridement of necrotic tissue was carried without improvement. Patient expired on 48th hospital day due to sepsis and impending hepatic coma.

MeSH Terms

Anti-Bacterial Agents
Debridement
Epidermis
Hepatic Encephalopathy
Hospitalization
Humans
Male
Middle Aged
Odors
Sepsis
Skin
Stevens-Johnson Syndrome*
Tetanus
Anti-Bacterial Agents