J Korean Neurol Assoc.  1994 Mar;12(1):152-158.

Radiation-Induced Lumbosacral Plexopathy: Clinical and Electrophysiological Findings in 3 Cases

Affiliations
  • 1Department of Neurology, College of Medicine, University of Ulsan, Korea.

Abstract

Radiation-induced neuropathy is a rare but well recognized clinical entity although peripheral nerves are considered to be relatively resistant to irradiation. We report three patients with radiation-induced lumbosacral plexopathy, whose characteristic clinical and electrophysiological features can be summarized as follows: 1) 55-58 year old women who were previously treated with radiotherapy for uterine cervix carcinoma: 2) the latent period is to 10 from 13 years: 3)predominantly motor involvement with slowly progressive paraparesis, asymmetrical onset and worse in distal muscle group: 4) painless at onset, with variable degree of sensorv changes: 5)decreased or absent knee and ankle jerks :6)axonal damage in electrophysiologic study: 7)frequent myokymic discharges. Myokymic discharges occur in bursts at regular rate of 0.1 to 8 Hz. In myokymic bursts with more spikes, interburst interval is longer but interspike Interval is shorter.


MeSH Terms

Ankle
Cervix Uteri
Female
Humans
Knee
Paraparesis
Peripheral Nerves
Radiotherapy
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