J Korean Ophthalmol Soc.  1978 Sep;19(3):265-272.

A Study on the Effect of Hibon in Arteriosclerotic Retinpathy, Diabetic Retinopathy and Cataract

• Kim JP
• Sohn MS

Abstract

Soon after the discovery of riboflavin, it was recognized that a deficiency of riboflavin was associated with disorders of lid, cornea, lens and retina. This study was devised to observe the effect of riboflavin on the metabolic changes in arteriosclerotic retinopathy, diabetic retinopathy and cataract. The experiment was carried out on 30 adult humans. After each case was treated with riboflavin, visual acuity, retinal change and cholesterol level in serum were determined. The result obtained from this experiment are summarzed as follows; 1. In Arteriosclerotic retinopathy, visual improvement is noted in 46% of 13 cases. Serum cholesterol level is decreased 32mg/dl in average. 2. In diabetic retinopathy, visual improvement is noted in 43% of 14 cases. Serum cholesterol level is slightly increased 0.9mg/dl in average. 3. In cataract, no visual improvement is noted. Serum cholesterol level is decreased 10.2mg/dl in average. 4. There was no known side effect during riboflavin therapy.

MeSH Terms

Adult
Cataract*
Cholesterol
Cornea
Diabetic Retinopathy*
Humans
Retina
Retinaldehyde
Riboflavin
Visual Acuity
Cholesterol
Retinaldehyde
Riboflavin