Korean J Pathol.  2006 Oct;40(5):373-376.

Solitary Cutaneous Reticulohistiocytoma On the Upper Lip: A Case Report

• Kim JW
• Kang HW

Abstract

Reticulohistiocytosis represents a rare spectrum of non-Langerhans cell histiocytosis: the solitary cutaneous form (reticulohistiocytoma), the diffuse or multiple cutaneous form without systemic involvement, and multicentric reticulohistiocytosis with systemic involvement. To the best of our knowledge, there have been relatively few reports in the literature of solitary cutaneous reticulohistiocytoma found on the lip. We report here on a case of solitary cutaneous reticulohistiocytoma in a 58-year-old male, who presented with an asymptomatic dome-shaped nodule adjacent to the upper lip. The histopathologic examination revealed a dense dermal infiltrate, that was composed predominantly of large oncocytic histiocytes and multinucleated giant cells with abundant granular eosinophilic cytoplasms, which had a "ground-glass" appearance.

Keyword

Reticulohistiocytoma; Lip

MeSH Terms

Cytoplasm
Eosinophils
Giant Cells
Histiocytes
Histiocytosis
Histiocytosis, Non-Langerhans-Cell*
Humans
Lip*
Male
Middle Aged