J Korean Neurol Assoc.
2003 Feb;21(1):111-114.
A Case of Hyperthyroid Myopathy Due to Graves' Disease
- Affiliations
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- 1Department of Neurology, Kangnung Asan Hospital, University of Ulsan College of Medicine, 415 Bangdong-ri, Sacheon-myon, Gangnung, Gangwon-do, 210-850, Korea. jkd@knh.co.kr
- 2Department of Internal Medicine, Kangnung Asan Hospital, University of Ulsan College of Medicine, Korea.
- 3Department of Diagnostic Pathology, Kangnung Asan Hospital, University of Ulsan College of Medicine, Korea.
- 4Department of Neurology, Seoul Asan Hospital, Asan Medical Center, University of Ulsan College of Medicine, Korea.
- 5Department of Family Medicine, Seoul Asan Hospital, Asan Medical Center, University of Ulsan College of Medicine, Korea.
Abstract
- A 49-year-old woman was admitted with a three-month history of myalgia and progressive proximal and distal muscle weaknesses. Physical examination showed diffuse enlargement of the thyroid gland and mild muscle atrophy. Serum creatine kinase was slightly increased and electromyography showed a myopathic pattern. Muscle biopsy showed nonspecific myopathic changes. Serum thyroid-stimulating hormone was very low, whereas thyroxine (T4) was greatly increased as well as anti-thyroglobulin, anti-microsome, and TSH-receptor antibody. The patient's symptoms were improved during the treatment with propilthiouracil.
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