Korean J Dermatol.  2005 Feb;43(2):244-248.

A Case of Squamous Cell Carcinoma Arising From an Inverted Papilloma in the Nasal Septum

• Jo JH
• Oh CK
• Son HS
• Kim MB
• Jang HS
• Kwon KS

Abstract

Inverted papillomas are uncommon benign epithelial tumors which typically occur on the lateral wall of the nose or paranasal sinuses. Inverted papilloma of the nasal septum account for between 5.5% and 16.7% of inverted papilloma. Histopathologically, these tumors show inversion of the neoplastic epithelium into the underlying stroma, rather than proliferating outwards. The tumors also demonstrate local aggressiveness, a high recurrence rate and the possibility of malignant transformation. Malignant transformation rate varies from 2% to 53%. But there is no clinical prognostic indicator to show the malignant potency of tumors. Therefore, early diagnosis and careful follow-up is very important. Some cases of this condition have been reported in otolaryngologic literature, but there are no reports of it in dermatologic literature. Herein we report a case of squamous cell carcinoma arising from an inverted papilloma in the nasal septum of a 78-year-old man.

Keyword

Inverted papilloma; Nasal septum; Squamous cell carcinoma

MeSH Terms

Aged
Carcinoma, Squamous Cell*
Early Diagnosis
Epithelium
Follow-Up Studies
Humans
Nasal Septum*
Nose
Papilloma, Inverted*
Paranasal Sinuses
Recurrence