Cancer Res Treat.  2005 Apr;37(2):129-132.

Lymph Node Metastases of Prostatic Adenocarcinoma in the Mesorectum in Patients with Rectal Cancer

Affiliations
  • 1Department of Surgery, University of Ulsan College of Medicine and Colorectal Clinic, Asan Medical Center, Seoul, Korea. jckim@amc.seoul.kr
  • 2Department of Urology, University of Ulsan College of Medicine and Colorectal Clinic, Asan Medical Center, Seoul, Korea.
  • 3Department of Pathology, University of Ulsan College of Medicine and Colorectal Clinic, Asan Medical Center, Seoul, Korea.

Abstract

Lymph node involvement is the most important prognostic factor of rectal cancer. Cancer originating from sites other than the rectum rarely metastasizes to the mesorectal lymph node. We report a rectal cancer patient with a synchronous metastatic prostatic carcinoma to the mesorectal lymph node.

Keyword

Mesorectal; Lymph node; Prostatic carcinoma

MeSH Terms

Adenocarcinoma*
Humans
Lymph Nodes*
Neoplasm Metastasis*
Rectal Neoplasms*
Rectum

Figure

  • Fig. 1 CT scan shows the encircling mass at the rectosigmoid junction. (A, B, C) An obstructing mass in the distal sigmoid colon. (D) Mass lesion in the prostate.

  • Fig. 2 Colonoscopy reveals the luminal-obstructing lesion in the distal sigmoid area.

  • Fig. 3 (A) The adenocarcinoma in the prostate, composed of cuboidal or columnar clear cells with a cribriform pattern. (B) The adenocarcinoma in the colon, with a complex glandular structures and pleomorphic columnar cells. (C) Right; The colonic adenocarcinoma metastasing to a lymph node. Left; The colonic adenocarcinoma is negative for PAP on immunostaining. (D) Right; The prostatic adenocarcinoma metastasizing to a lymph node. Left; The prostatic adenocarcinoma is positive for PAP on immunostaining.


Reference

1. Jones H, Anthony PP. Metastatic prostatic carcinoma presenting as left-sided cervical lymphadenopathy: a series of 11 cases. Histopathology. 1992; 21:149–154. PMID: 1505932.
Article
2. Mourra N, Pare Y, McNamara D, Tiret E, Flejou JF, Parc R. Lymph node metastases of prostatic adenocarcinoma in the mesorectum in patients with adenocarcinoma or villous tumor of the rectum with collision phenomenon in a single lymph node: report of five cases. Dis Colon Rectum. 2005; online first.
Article
3. Smith MJ. The lymphtics of the prostate. Invest Urol. 1966; 3:439–444. PMID: 4160189.
4. McLaughlin AP, Saltzstein SL, McCullough DL, Gittes RF. Prostatic carcinoma: incidence and location of unsuspected lymphatic metastasis. J Urol. 1976; 115:89–94. PMID: 1246119.
5. Wibur DC, Krenaer K, Bonfiglio TA. Prostatic specific antigen (PSA) staining in carcinoma of non prostatic origin. Am J Clin Pathol. 1987; 12:530.
6. May EE, Perentes E. Anti-Leu 7 immunoreactivity with human tumors: its value in the diagnosis of prostatic adenocarcinoma. Histopathology. 1987; 11:295–304. PMID: 2448219.
7. Herman E, Elfont E, Boenisch T. Prostate-specific antigen. Histopathology. 1988; 12:687–688. PMID: 2458311.
Article
8. Stearns MW Jr, Deddish MR. Five-year results of abdominopelvic lymph node dissection for carcinoma of the rectum. Dis Colon Rectum. 1959; 2:169–172. PMID: 13652786.
Article
9. Moriya Y, Hojo K, Sawada T, Koyama Y. Significance of lateral node dissection for advanced rectal carcinoma at or below the peritoneal reflection. Dis Colon Rectum. 1989; 32:307–315. PMID: 2784376.
Article
10. Kapiteijn E, Marijnen CA, Nagtegaal ID, Putter H, Steup WH, Wiggers T, et al. Preoperative radiotherapy combined with total mesorectal excision for respectable rectal cancer. N Engl J Med. 2001; 345:638–646. PMID: 11547717.
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