Korean J Otolaryngol-Head Neck Surg.  1998 Jul;41(7):918-924.

The Non-Squamous Cell Tumors of the Larynx

Affiliations
  • 1Department of Otolaryngology-Head and Neck Surgery, School of Medicine, The Catholic University of Korea, Seoul, Korea. htkim@cmc.cuk.ac.kr

Abstract

BACKGROUND AND OBJECTIVES: The majority of laryngeal tumors are known to be squamous cell carcinoma. Non-squamous cell tumors of the larynx represent various spectrum of diseases with different prognosis and rationales of management from squamous cell carcinoma. Therapeutic options to these tumors depend on their histopathological characteristics and clinical behavior. To assess the unique aspects of the non-squamous cell tumors which can lead to their diagnosis and to provide considerations of management options and prognostic variables.
MATERIALS AND METHODS
Eight non-squamous cell tumors of the larynx including 6 malignant tumors (two malignant lymphoma, single instances of adenoid cystic carcinoma, malignant schwanoma, osteosacoma, and spindle cell carcinoma) and two benign tumor (hemangioma, spindle cell lipoma) during the 7-year period from 1990 to 1996 were reviewed retrospectively.
RESULTS
The frequently presenting symptoms were hoarseness, dyspnea, sore throat, and lump sensation in the throat. The most common origin site was supraglottis (50%), followed by glottis (38%) and subglottis (12%). All non-squamous malignancies beside non-Hodgkin's lymphoma were treated by surgery and postoperative radiotherapy. Two benign tumors were treated with only surgery. The mean follow-up period was 37.4 months and all patients have survivied with no evidence of recurrence.
CONCLUSION
Our experience suggests that non-squamous cell tumors are a group of various pathological types and it may be possible to achieve better results with combined treatment including surgery.

Keyword

Larynx; Non-squamous cell tumors

MeSH Terms

Carcinoma, Adenoid Cystic
Carcinoma, Squamous Cell
Diagnosis
Dyspnea
Follow-Up Studies
Glottis
Hoarseness
Humans
Larynx*
Lymphoma
Lymphoma, Non-Hodgkin
Pharyngitis
Pharynx
Prognosis
Radiotherapy
Recurrence
Retrospective Studies
Sensation
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