Diffuse Idiopathic Skeletal Hyperostosis in Koreans 9 Cases Report

Lee, Myong Ho; Jung, Sung Soo; Hong, Kwan Pyo; Kim, Tae Hwan; Jun, Jae Bum; Lee, In Hong; Bae, Sang Cheol; Yoo, Dae Hyun; Kim, Seong Yoon; Kim, Mok Hyun

Abstract

OBJECT: To investigate the characteristics of diffuse idiopathic hyperostosis (DISH) in Koreans.
METHODS
The nine patients of DISH were investigated in terms of symptom, involved area in simple X-ray, accompaning disease, serum uric acid level, and serum triglyceride and cholesterol.
RESULTS
Eight of nine patients were male, one patient was female, and their mean age was 64. Their symptoms were no symptom(2/9), neck pain(2/9), dorsal pain(2/9), and low back pain(3/9). The involved areas were the cervical vertebrae(1/9), the lower thoracic vertebrae(3/9), or the lower thoracic and upper lumbar vertebrae(5/9). The accompaning diseases were ankylosing spondylitis (1/9), degenerat,ive joint disease (2/9), posterior laminectomy (1/9), diabetes mellitus (1/9), chronic active hepatitis (1/9), cerebrovascular accident (2/9), hypertension(2/9), chronic renal failure(2/9), and gout(2/9). In the cases involving thoracic vertebrae, the ossification was seen dominantly in the right side. Four of nine patients had diabetes mellitus, hyperuricemia (7. 0 mg/dl in male and 6.6 mg/dl in female), or dyslipidemia (194 mg/dl in serum triglycerid level and 275 mg/dl in serum cholesterol level).
CONCLUSIONS
In our cases of DISH, it was dominant in male and old age, and the diabetes mellitus or hyperuricemia was more frequently found than in general population.