J Korean Surg Soc.  2007 Aug;73(2):178-182.

Neuroendocrine Tumor of the Colon

• Jeong MH
• Kang BW
• Son CM
• Kim HS

Abstract

Neuroendocrine tumor (NET) of the colon and rectum has been reported to have a low incidence and aggressive progression; it is frequently misdiagnosed and its treatment is not well documented. Four NET cases were collected at our hospital during the previous year of a colon cancer survey. Endoscopic mucosal biopsy of the colon was done for each case and all the cases proved to be adenocarcinomas. Curative surgery was conducted after the preoperative diagnostic and staging evaluation was completed. The locations of the primary lesions of the patients were all different; cecum, ascending colon, splenic flexure colon and sigmoid colon. The disease was advanced in all cases and the first postoperative diagnosis was poorly differentiated adenocarcinoma. Immunohistochemical tests followed and all the cases were positive for chromogranin A staining. A retrospective study was then conducted.

Keyword

Neuroendocrine tumor; Colon; Immunohistochemical stain

MeSH Terms

Adenocarcinoma
Biopsy
Cecum
Chromogranin A
Colon*
Colon, Ascending
Colon, Sigmoid
Colon, Transverse
Colonic Neoplasms
Diagnosis
Humans
Incidence
Neuroendocrine Tumors*
Rectum
Retrospective Studies
Chromogranin A