Chonnam Med J.
2003 Dec;39(4):239-243.
Clinical Analysis of 47 Paraquat-Intoxicated Patients Treated with Hemoperfusion
- Affiliations
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- 1Department of Internal Medicine, Seonam University College of Medicine, Korea. Ismed@hanmail.net
Abstract
- Paraquat was developed as a herbicide in England in 1958. It is now sold as Gramoxone(r) & Paraco(r) in Korea. Acute paraquat poisoning is notorious for its fatal outcome. Even though many studies have focused on successful treatment modality, no standard treatment has been established so far. The authors analysed 47 cases of paraquat intoxication who were treated with hemoperfusion in Seonam University Hospital from June 2000 to April 2003. In most patients, hypothermia, tachypnea, decreased in pH and PaCO2 with the increases in white blood cell count and anion gap were seen. Patients with fatal outcome showed significant increases in aspartate transferase, blood urea mitrogen and creatinine and decreases in amylase, along with increased plasma paraquat level.
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