Korean J Gastrointest Endosc.
2008 Feb;36(2):102-106.
A Case of Primary B Cell Mucosa-associated Lymphoid Tissue Lymphoma Presenting as a Solitary Rectal Mass
- Affiliations
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- 1Department of Internal Medicine, Inje University Ilsan Paik Hospital, Goyang, Korea. ymoon@ilsanpaik.ac.kr
- 2Department of Pathology, Inje University Ilsan Paik Hospital, Goyang, Korea.
- 3Department of Internal Medicine, Incheon Choongang General Hospital, Incheon, Korea.
Abstract
- Primary extranodal B cell lymphoma of mucosa- associated lymphoid tissue (MALT) can develop in diverse anatomic locations such as the stomach, salivary gland, thyroid, lung, and breast. Its distribution in the GI tract is as follows: 50~60% in the stomach, 20~30% in the small intestine and ileocecal area and 10% in the colorectal area. Although autoimmune and infectious diseases are known as the main etiologies, H. pylori infection has been clearly shown to play a causative role in lymphomagenesis, especially in the stomach. H. pylori eradication therapy only can induce disease remission nearly in 80% of the cases of gastric MALT lymphoma. However, there is lack of evidence for the extragastric area. In this case, a 71-year-old woman with low abdominal pain was diagnosed as having a rectal MALT lymphoma that was noted as a solitary rectal mass in a colonoscopic examination. Remission induction was commenced by H. pylori eradication and radiation therapy.