Nucl Med Mol Imaging.  2008 Apr;42(2):172-180.

Motion Correction in PET/CT Images

  • 1Molecular Imaging Research Center, Radiological and Medical Sciences Research Institute, Korea Institute of Radiological and Medical Sciences, Seoul, Korea.


PET/CT fused image with anatomical and functional information have improved medical diagnosis and interpretation. This fusion has resulted in more precise localization and characterization of sites of radio-tracer uptake. However, a motion during whole-body imaging has been recognized as a source of image quality degradation and reduced the quantitative accuracy of PET/CT study. The respiratory motion problem is more challenging in combined PET/CT imaging. In combined PET/CT, CT is used to localize tumors and to correct for attenuation in the PET images. An accurate spatial registration of PET and CT image sets is a prerequisite for accurate diagnosis and SUV measurement. Correcting for the spatial mismatch caused by motion represents a particular challenge for the requisite registration accuracy as a result of differences in PET/CT image. This paper provides a brief summary of the materials and methods involved in multiple investigations of the correction for respiratory motion in PET/CT imaging, with the goal of improving image quality and quantitative accuracy.


PET/CT; motion; registration; motion correction; respiratory motion; attenuation correction

MeSH Terms

Positron-Emission Tomography and Computed Tomography
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