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J Clin Neurol.  2010 Dec;6(4):212-215. 10.3988/jcn.2010.6.4.212.

Transient Increase in Intrathoracic Pressure as a Contributing Factor to Cardioembolic Stroke

Affiliations
  • 1Department of Neurology, Guro Hospital, College of Medicine, Korea University, Seoul, Korea. nukseo@korea.ac.kr

Abstract

BACKGROUND
The hemodynamic effects of increased intrathoracic pressure (ITP) have been the focus of many investigations. However, very little is known about the effects of elevated ITP on the occurrence of stroke.
CASE REPORT
Four young patients with a cardioembolic source of stroke were examined. In all cases the stroke was preceded by an increase in ITP that occurred during coughing, vomiting, or sexual intercourse.
CONCLUSIONS
We suggest that cardioembolic stroke is facilitated by situations in which ITP is elevated.

Keyword

stroke; intrathoracic pressure; embolism

MeSH Terms

Cough
Embolism
Hemodynamics
Humans
Stroke
Vomiting
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