Korean J Dermatol.
2011 Jun;49(6):533-537.
Epidermal Necrolysis due to Methazolamide Treatment in Glaucomatous Patients
- Affiliations
-
- 1Department of Dermatology, Chosun University Medical School, Gwangju, Korea. kcchoi@chosun.ac.kr
Abstract
- Epidermal necrolysis (EN) is a rare, but potentially life threatening disease, characterized by epidermal necrosis and sub-epidermal detatchment, and is predominantly medication-induced. Methazolamide is a sulfonamide derivative and carbonic anhydrase inhibitor used for lowering of intraocular pressure in glucomatous patients. Common side effects of methazolamide include metabolic acidosis, hypokalemia, tinnitus, transient myopia, and renal calculi; however, EN caused by methazolamide is very rare. We report on two cases of EN induced by methazolamide treatment and review previously published cases.
Keyword
- Full Text Links
-
- Actions
-
Cited
- CITED
-
- Close
- Share
-
- Similar articles
-
- Two Cases of HLA-B59(+) Stevens-Johnson Syndrome (SJS)-Toxic Epidermal Necrolysis (TEN) Associated with Methazolamide Treatment
- Methazolamide-induced toxic epidermal necrolysis confirmed by lymphocyte activation test
- Toxic Epidermal Necrolysis and Stevens-Johnson Syndrome Caused by Topical Ophthalmic Use of Dorzolamide
- Methazolamide-induced Stevens-Johnson Syndrome
- A Case of Toxic Epidermal Necrolysis Due to Contact of Paraquat(Gramoxone(R))
