Korean J Thorac Cardiovasc Surg.  2011 Apr;44(2):131-136. 10.5090/kjtcs.2011.44.2.131.

Aortic Valve Replacement for Aortic Stenosis and Concomitant Coronary Artery Bypass: Long-term Outcomes and Predictors of Mortality

Affiliations
  • 1Department of Thoracic and Cardiovascular Surgery, Asan Medical Center, University of Ulsan College of Medicine, Korea. jwlee@amc.seoul.kr
  • 2Department of Thoracic and Cardiovascular Surgery, Gangneung Asan Hospital, University of Ulsan College of Medicine, Korea.

Abstract

BACKGROUND
We evaluated the surgical results and predictors of long-term survival in patients who underwent coronary artery bypass grafting (CABG) at the time of an aortic valve replacement (AVR) due to aortic stenosis.
MATERIALS AND METHODS
Between January 1990 and December 2009, 183 consecutive patients underwent CABG and concomitant aortic valve replacement for aortic stenosis. The mean follow-up period was 59.8+/-3.3 months and follow-up was possible in 98.3% of cases. Predictors of mortality were determined by Cox regression analysis.
RESULTS
There were 5 (2.7%) in-hospital deaths. Follow-up of the in-hospital survivors documented late survival rates of 91.5%, 74.8%, and 59.6% at 1, 5, and 10 postoperative years, respectively. Age (p<0.001), a glomerular filtration rate (GFR) less than 60 mL/min (p=0.006), and left ventricular (LV) mass (p<0.001) were significant predictors of mortality in the multivariate analysis.
CONCLUSION
The surgical results and long-term survival of aortic valve replacement with concomitant CABG in patients with aortic stenosis and coronary artery disease were acceptable. Age, a GFR less than 60 mL/min, and LV mass were significant predictors of mortality.

Keyword

Aortic valve stenosis; Coronary artery disease; Coronary artery bypass surgery

MeSH Terms

Aortic Valve
Aortic Valve Stenosis
Coronary Artery Bypass
Coronary Artery Disease
Coronary Vessels
Follow-Up Studies
Glomerular Filtration Rate
Humans
Survival Rate
Survivors
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